Analysis of Radial Patterning in Arabidopsis

拟南芥径向图案分析

• 批准号: 0922678
• 负责人: Frans Tax
• 金额: $ 30万
• 依托单位: University of Arizona
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2013-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0922678&HistoricalAwards=false
• 关键词: Analysis; Radial; Patterning; Arabidopsis

PI: Frans E. Tax Proposal number: IOS-0922678Title: Analysis of Radial Patterning in ArabidopsisThis award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5)Radial patterning is a fundamental process in the development of all plants. Roots, stems, and flowers exhibit a radial pattern of organization, and this pattern is formed in the early embryo. The goal of this project is to understand how plant tissues become organized as concentric layers of cells. Since the generation of layers of cells is expected to require communication between cells, mutants in receptors would be predicted to affect radial pattern in embryos, when layers of cells are first established. Double mutants for two receptors in the model plant Arabidopsis were found to change outer cell types to inner cell types in the embryo. In this project, the hypothesis that the outer layer of the embryo acts as an organizer and regulates the identity of inner layers will be tested. Using genetic and biochemical approaches, candidate signals for these receptors and proteins that these receptors act on will be characterized. This project will provide a framework for understanding the signaling mechanisms responsible for radial patterning in plants, which is currently not well understood. The results from this project can be applied to regulating important traits such as stem size, root growth and male sterility in crop plants. This project will contribute to the training of graduate students, undergraduates and high school students and teachers in plant development, genetics and genomics. A teacher will be recruited the first summer to develop a plant genetics or genomics-based unit, will implement the unit during the school year, and refine it during a second summer.

PI：Frans E.税务提案编号：IOS-0922678标题：拟南芥辐射状图案分析该奖项由2009年美国复苏和再投资法案（公法111-5）资助。辐射状图案是所有植物发育的基本过程。根、茎和花表现出放射状的组织模式，这种模式在早期胚胎中形成。该项目的目标是了解植物组织如何组织成同心细胞层。由于细胞层的产生预计需要细胞之间的通信，当细胞层首次建立时，受体中的突变体将被预测影响胚胎中的放射状图案。在模式植物拟南芥中发现两种受体的双突变体在胚胎中将外细胞类型改变为内细胞类型。 在该项目中，将测试胚胎外层充当组织者并调节内层身份的假设。 使用遗传和生化方法，将表征这些受体的候选信号以及这些受体作用的蛋白质。该项目将提供一个框架，用于理解负责植物辐射图案的信号机制，这是目前还没有很好地理解。该项目的结果可应用于调节作物的重要性状，如茎的大小，根的生长和雄性不育。该项目将有助于对研究生、本科生和高中生以及教师进行植物发育、遗传学和基因组学方面的培训。第一个夏天将招募一名教师开发一个植物遗传学或基因组学为基础的单元，将在学年期间实施该单元，并在第二个夏天对其进行完善。