MRI: Acquisition of an Atomic Force Microscope (AFM) for Visualization, Assembly, and Analysis of Materials at the Nanometer and Molecular Scale

MRI：获取原子力显微镜 (AFM)，用于纳米和分子尺度材料的可视化、组装和分析

• 批准号: 0923066
• 负责人: Richard Vinci
• 金额: $ 24.95万
• 依托单位: Lehigh University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-10-01 至 2012-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0923066&HistoricalAwards=false
• 关键词: MRI; Acquisition; Atomic; Force; Microscope

0923066VinciLehigh U."This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5)."Technical AbstractA flexible Atomic Force Microscope (AFM), integrated with an inverted light microscope, enables advanced nanometer scale imaging, spectroscopy, lithography, and manipulation. Acquisition of this instrument will: (i) significantly improve the capability at Lehigh University to characterize surfaces and interfaces, as well as new nanometer-scale materials; (ii) promote fundamental studies of intermolecular interactions, self-assembly, and nanofabrication; (iii) help develop new analytical techniques; (iv) allow the current, old, shared AFM/nanoindenter to be dedicated to full-time nanoindentation, and (v) enhance collaborations developing on campus among academic units such as Physics, Chemistry, Materials Science, and Chemical Engineering. Fundamental research that will be carried out with a new state-of-the-art AFM will advance understanding of molecular and nanometer scale mechanics and biomolecular interactions, self-assembly and organization at the nanoscale, as well as synthesis, manipulation, and properties of new, complex nanostructures (such as macroions, calix[6]arene Langmuir-Blodgett films, and carbon nanotube-DNA hybrids). It will also enable increased campus-wide use of nanoindentation, thereby supporting ongoing work in nano- and micro-mechanics of metals, ceramics, and composites. The diverse nature of studies that can be carried out using a modern AFM will contribute greatly to the interdisciplinary effort required to train students and post-doctoral researchers to work at the interfaces between chemistry, physics, biology, and engineering, and will improve collaborations with external academic, business and industrial partners. Outreach to students at the professional, undergraduate, and K-12 levels will be enhanced by the instrument?s ease of use and remote operation capability.Non-technical AbstractAn Atomic Force Microscope (AFM) coupled to an optical microscope can be used to visualize, measure, and manipulate surfaces at the nanometer scale. This capability is crucial for understanding and modifying the phenomena that underlie processes such as catalysis for chemical production, adhesion of cells for development of new biomaterials, and growth of nanostructures for advanced lighting devices. With an AFM it is possible to analyze a wide variety of materials ? from soft to hard, organic to inorganic, wet to dry ? with atomic resolution. Furthermore, the ability to actually manipulate matter at the nanoscale creates new possibilities for the creation and testing of unique materials, including complex molecules and carbon nanotube-DNA hybrids, that could solve problems in diverse areas such as energy production, space exploration, and disease treatment. With accessories that establish the conditions necessary for the examination of biological materials, the instrument will enable new directions in nanotechnology research at Lehigh University in Bioengineering, Physics, Chemistry, Materials Science, and Chemical Engineering. The new capability will also enable increased use of an old, existing AFM as a dedicated nanomechanical test instrument for understanding the failure resistance of novel nanomaterials. The new instrument will be much easier to use than those of previous generations, so it will be more accessible to undergraduate students and industry collaborators. It can also be operated over the Web, and can be used at a distance to engage children at the K-12 levels by allowing them to ?see? at the nanoscale without leaving their classrooms.

0923066 vincilehigh U。“这项奖励是根据2009年美国复苏和再投资法案（公法111-5）资助的。”技术摘要：柔性原子力显微镜（AFM）与倒置光学显微镜集成，可实现先进的纳米级成像、光谱学、光刻和操作。获得该仪器将：(i)显著提高利哈伊大学表征表面和界面以及新型纳米尺度材料的能力；（ii）促进分子间相互作用、自组装和纳米制造的基础研究；（iii）帮助开发新的分析技术；（iv）允许现有的、旧的、共享的AFM/纳米压痕机专门用于全职纳米压痕；(v)加强物理、化学、材料科学和化学工程等学术单位在校园内的合作。基础研究将采用最先进的原子力显微镜进行，这将促进对分子和纳米尺度力学、生物分子相互作用、纳米尺度上的自组装和组织，以及新的复杂纳米结构（如宏离子、杯[6]芳烃Langmuir-Blodgett膜和碳纳米管- dna杂化物）的合成、操作和性质的理解。它还将使纳米压痕在校园范围内的使用增加，从而支持正在进行的金属、陶瓷和复合材料的纳米和微观力学工作。使用现代原子力显微镜进行的研究的多样性将极大地促进跨学科的努力，培养学生和博士后研究人员在化学、物理、生物和工程之间的界面工作，并将改善与外部学术、商业和工业伙伴的合作。与专业、本科和K-12年级学生的接触将通过该仪器得到加强。S易于使用和远程操作能力。摘要原子力显微镜（AFM）与光学显微镜相结合，可以在纳米尺度上对表面进行可视化、测量和操作。这种能力对于理解和修改过程中潜在的现象至关重要，如化学生产的催化，开发新生物材料的细胞粘附，以及用于先进照明设备的纳米结构的生长。AFM可以分析各种各样的材料。从软到硬，从有机到无机，从湿到干？原子分辨率。此外，在纳米尺度上实际操作物质的能力为创造和测试独特材料创造了新的可能性，包括复杂分子和碳纳米管- dna杂交，这可以解决能源生产、太空探索和疾病治疗等不同领域的问题。该仪器将为利哈伊大学在生物工程、物理、化学、材料科学和化学工程等领域的纳米技术研究开辟新的方向。新功能还将增加旧的现有AFM作为专用纳米力学测试仪器的使用，以了解新型纳米材料的抗破坏能力。新仪器将比前几代仪器更容易使用，因此它将更容易被本科生和行业合作者使用。它也可以在网络上操作，可以远程使用，让K-12年级的孩子们“看到”。在纳米尺度上，不用离开教室。