MRI: Acquisition of Instrumentation for Proteomics Research or Training Encompassing Investigators' Needs Lab at SJSU (PROTEIN Lab)

美国国家科学基金会已向圣何塞州立大学（SJSU）提供资金，用于开发蛋白质组学设施。该项目的目标是转变和扩大SJSU的分子生命科学研究能力。这是化学和生物系教师之间的合作努力，以促进两个部门之间的机构联系，除了目前存在的一对一的联系。这一目标将通过在SJSU建立蛋白质实验室，发展分子生命科学研究的教师专业知识，并在蛋白质组学研究中培训SJSU学生来实现。 该计划将实现各种科学进步，包括识别生物信号转导途径中的新型蛋白质，表征来自不同生物来源的新型蛋白质，如不可培养的细菌到人类，纯化蛋白质用于蛋白质拥挤和水合作用的生物物理研究，以及表征小分子。该计划将提高生物学和化学系的研究能力，促进使用蛋白质设施的研究人员之间的合作，并为研究生和本科生过渡到研究生/专业课程或湾区的生物技术工作队伍做好准备。 研究项目的结果将发表在同行评审的期刊上，并通过学生和教师在区域或国家会议上的演讲进行传播。

The National Science Foundation has awarded San José State University (SJSU) funds to develop a proteomics facility. The goal of this project is to transform and expand the molecular life sciences research capabilities at SJSU. This is a collaborative effort between faculty in the Departments of Chemistry and Biology to foster institutional linkages between the two departments in addition to the one-on-one linkages that currently exist. This goal will be accomplished through the establishment of the PROTEIN Lab at SJSU, developing faculty expertise in molecular life science research, and training SJSU students in proteomics research. This program will enable a variety of scientific advances, including identification of novel proteins in biological signal transduction pathways, characterization of novel proteins from diverse biological sources such as uncultivable bacteria to humans, purification of proteins for biophysical studies of protein crowding and hydration effects, and characterization of small molecules. This program will enhance the research capabilities in the Departments of Biology and Chemistry, stimulate collaboration amongst researchers who use the PROTEIN facility, and prepare graduate and undergraduate students for transition to graduate/professional programs or the biotechnology work force in the Bay Area. Results from the research projects will be published in peer-reviewed journals, and disseminated through presentations by students and faculty at regional or national meetings.