MRI-R2: Acquisition of UV-Vis-NIR, FT-IR, and Fluorescence Spectrometric Instrumentation

该奖项是根据2009年美国复苏和再投资法案（公法111-5）资助的。巴纳德学院的Marisa Buzzeo、John S. Magyar、Dina C. Merrer、Christian M. Rojas和Alison P. Williams将获得一个高分辨率紫外-可见-近红外（UV-Vis-NIR）光谱仪、一个高分辨率傅立叶变换红外（FT-IR）光谱仪和一个荧光光谱仪。这些仪器将被化学系的所有研究活跃成员及其在生物物理、环境生物无机、合成有机和物理有机化学方面的研究生使用。在这三种光谱工具的帮助下，本科生将能够在以下领域进行研究：电化学生物传感和药物膜相互作用；组织防腐剂福尔马林对DNA损伤的机制；海洋微生物金属调控蛋白的金属结合热力学、配位化学和构象动力学叠氮甲酸酯生成金属络合酰基亚硝基并研究了卤代烃与应变环有机底物的生成和反应性。光谱学是一种分析技术，它利用各种波长的光（电磁辐射）来探测物质的结构和组成。辐射可以被差分吸收，产生吸收光谱，或者被吸收后发射，产生发射光谱或荧光光谱。吸收或发射随波长变化的变化提供了材料的光谱特征，有时称为指纹。这些光谱仪将用于本科生的研究和实验课程，提供化学和生物实验中定量和定性分析所必需的基本技术培训。

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).With this award from the Major Research and Instrumentation (MRI) program, Marisa Buzzeo, John S. Magyar, Dina C. Merrer, Christian M. Rojas and Alison P. Williams of Barnard College will acquire a high-resolution ultraviolet-visible-near-infrared (UV-Vis-NIR) spectrometer, a high-resolution Fourier transform infrared (FT-IR) spectrometer, and a fluorescence spectrometer. These instruments will be used by all research-active members of the Chemistry Department and their research students in biological physical, environmental bioinorganic, synthetic organic, and physical organic chemistry. With the aid of these three spectroscopic tools, undergraduates will be able to conduct research in the following areas: electrochemical biosensing and drug-membrane interactions; mechanisms of DNA damage by the tissue preservative, formalin; metal-binding thermodynamics, coordination chemistry, and conformational dynamics of metalloregulatory proteins in marine microorganisms; formation of metal-complexed acyl nitrenes from azidoformates; and, generation and reactivity of halocarbenes with strained cyclic organic substrates.Spectroscopy is an analytical technique that uses light (electromagnetic radiation) of various wavelengths to probe the structure and composition of matter. The radiation may be absorbed differentially producing an absorption spectrum or absorbed and later emitted producing an emission or fluorescence spectrum. The variation of the absorption or emission as the wavelength is changed provides a spectrum characteristic of the material, sometimes called a fingerprint. These spectrometers will be used by undergraduates in research and laboratory courses providing training in this basic technique essential to quantitative and qualitative analysis in chemistry and biological experiments.