MRI-R2: Nano Photonic Imaging System

MRI-R2：纳米光子成像系统

• 批准号: 0960331
• 负责人: Dirk Bouwmeester
• 金额: $ 46.47万
• 依托单位: University of California-Santa Barbara
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-03-15 至 2013-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0960331&HistoricalAwards=false
• 关键词: MRI; R2; Nano; Photonic; Imaging

0960331BouwmeesterU. of California-Santa BarbaraTECHNICAL ABSTRACT: This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). A rapidly expanding field of research concerns the development of new techniques for optical imaging of nanometer to micron scale structures, such as biological molecules with integrated functional elements, semiconductor optoelectronic devices and cells. The investigator team proposes to develop an unconventional optical instrument capable of resolving structures on the scale of a few tens of nanometers, by using special correlated states of light (such as entangled two-photon states) in combination with an ultra stable optical platform with nanometer resolution scanning capabilities and recently-developed signal processing algorithms. In order to probe the special light-matter interactions that occur when phonon-induced dephasing is minimal, the system is designed to operate at cryogenic as well as ambient temperatures. The wide wavelength range of this nano-photonics imaging system would enable investigation of structures ranging from semiconductor nanodevices to DNA scaffolds to living cells. The research team consists of experts in the key technological aspects: quantum optics, high resolution optical imaging and high speed image processing, ultra-low vibration and low-temperature operation, and biological system design.LAYMAN ABSTRACT: This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Finding ways to use light to probe smaller and smaller structures, down to the tens of nanometer (nm) sizes of emerging synthetic DNA structures and the molecular machines within cells, is of enormous importance for current and future developments in science, technology, and medicine. Because traditional light microscopes can't see structures smaller than a few hundreds of nm, most of today's sub-micron imaging is done using non-optical, atomic force and electron microscopes, which can damage or obscure delicate structures within cells and nanodevices. To achieve high resolution together with the gentle, non-invasive imaging provided by light, the scientific team proposes to build a new type of optical instrument. The features that offer greatly improved resolution, of just a few tens of nm, are use of very special quantum-correlated states of light combined with high stability scanning methods and advanced data processing algorithms. To enable imaging of a wide range of nanoscale systems, the instrument will operate over a large range of light wavelengths, both at room temperature and at the much colder temperatures needed to prevent thermal agitation from degrading special quantum effects of the light on the tiniest, molecular-scale structures. The research team has the appropriate expertise in spectroscopic techniques, quantum optics and cryogenics techniques to be successful in developing this advanced nano-photonic, variable-temperature imaging instrument.

0960331 Bouwmeester U.加州大学圣巴巴拉分校技术摘要：该奖项由《2009年美国复苏和再投资法案》(公法111-5)资助。一个迅速发展的研究领域涉及到纳米到微米级结构光学成像新技术的发展，如具有集成功能元件的生物分子、半导体光电子器件和细胞。研究团队建议，通过使用特殊的光关联状态(如纠缠双光子状态)，结合具有纳米分辨率扫描能力的超稳定光学平台和最近开发的信号处理算法，开发一种能够分辨几十纳米级结构的非传统光学仪器。为了探测声子引起的退相最小时发生的特殊光-物质相互作用，该系统被设计为在低温和环境温度下工作。这种纳米光子学成像系统的宽波长范围将使从半导体纳米器件到DNA支架再到活细胞的结构研究成为可能。该研究团队由量子光学、高分辨率光学成像和高速图像处理、超低振动和低温操作以及生物系统设计等关键技术方面的专家组成。莱曼摘要：该奖项是根据2009年美国复苏和再投资法案(公共法律111-5)资助的。寻找利用光来探测越来越小的结构，小到几十纳米(Nm)的新兴合成DNA结构和细胞内的分子机器的方法，对当前和未来的科学、技术和医学发展具有极其重要的意义。由于传统的光学显微镜无法看到小于几百纳米的结构，今天的大多数亚微米成像都是使用非光学、原子力和电子显微镜进行的，这可能会破坏或掩盖细胞和纳米设备中的微妙结构。为了实现高分辨率以及光提供的温和、非侵入性成像，该科学团队提出建造一种新型光学仪器。提供极大提高分辨率的功能，仅为几十纳米，使用非常特殊的量子相关光状态，结合高稳定性扫描方法和先进的数据处理算法。为了能够对广泛的纳米级系统进行成像，该仪器将在大范围的光波长上运行，无论是在室温下还是在更低的温度下，以防止热搅拌降低光在最微小的分子级结构上的特殊量子效应。研究团队在光谱技术、量子光学和低温技术方面拥有适当的专业知识，能够成功开发这种先进的纳米光子变温成像仪器。