Radford University Department of Biology and Chemistry Facilities Modernization

雷德福德大学生物与化学系设施现代化

• 批准号: 0963298
• 负责人: H. Francis Webster
• 金额: $ 39.98万
• 依托单位: Radford University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-10-01 至 2013-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0963298&HistoricalAwards=false
• 关键词: Radford; University; Department; Biology; Chemistry

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).This project will renovate laboratory space in Curie Hall on the campus of Radford University to create core research facilities for the university's biology and chemistry programs. This renovation is needed to allow more students to participate in undergraduate research, improve the quality and scope of the research activities of the faculty and students, provide a safer work environment, and increase collaborative efforts between the biology and chemistry programs. The majority of the research space in the building has not been renovated since its original construction nearly 40 years ago. For the biology research program, the renovation will provide a core research facility in the basement of Curie Hall with two vivariums and reconfigured space for shared research instrumentation. On the third floor of Curie Hall, a core laboratory will be created for collaborative research in chemistry and biochemistry. Faculty in the renovated core labs will conduct research and research training in the areas of biology, microbiology, cellular and molecular biology, biochemistry, chemical kinetics and catalysis, analytical chemistry, and neuroscience. Examples of research activities proposed for the renovated laboratories include studies of the neural mechanisms that regulate appetite in an animal model, actions of the neuroendocrine and immune systems, and their impact on behavior and cognition, in free living species, investigation of the enzyme beta-glucuronidase which catalyzes the cleavage of a glucuronide group from substrates and has major implications in human health and cancer therapeutics, and development of a new catalyst for esterification and transesterification reactions related to biodiesel production.With the core facilities for biology and chemistry research, the Biology and Chemistry Department will be able to continue its dedication to excellence in undergraduate research and education through one-on-one student/faculty mentoring. The university serves a diverse and motivated undergraduate population, which includes a significant number of first-generation college students. The renovation project will provide better laboratories to inspire more of these undergraduate students through research to pursue graduate and professional post-baccalaureate education.

该奖项是根据2009年美国复苏和再投资法案(公法111-5)资助的。该项目将翻新雷德福大学校区居里厅的实验室空间，为该大学的生物和化学项目创建核心研究设施。这项改革是为了让更多的学生参与本科生的研究，提高教职员工和学生的研究活动的质量和范围，提供更安全的工作环境，以及加强生物和化学专业之间的协作。这座建筑中的大部分研究空间自近40年前最初建造以来一直没有翻新。对于生物学研究计划，翻新将在居里厅地下室提供一个核心研究设施，有两个隔室，并重新配置空间，用于共享研究仪器。在居里厅的三楼，将创建一个核心实验室，用于化学和生物化学的合作研究。翻新后的核心实验室的教职员工将在生物学、微生物学、细胞和分子生物学、生物化学、化学动力学和催化、分析化学和神经科学等领域进行研究和研究培训。建议用于翻新实验室的研究活动包括：在动物模型中研究调节食欲的神经机制，在自由生命物种中研究神经内分泌和免疫系统的行为及其对行为和认知的影响，研究催化葡萄糖醛酸基从底物中分解并对人类健康和癌症治疗具有重大影响的酶β-葡萄糖醛酸苷酶，以及开发与生物柴油生产相关的酯化和酯交换反应的新催化剂。有了生物和化学研究的核心设施，生物和化学系将能够通过一对一的学生/教师指导继续致力于本科生研究和教育。这所大学服务于多元化和积极的本科生群体，其中包括相当数量的第一代大学生。翻新项目将提供更好的实验室，通过研究激励更多的本科生攻读研究生和专业学士学位后教育。