2010 Gordon Research Conference on the Biology Post-Transcriptional Gene Regulation to be held July 18 through July 23, 2010; Newport, R.I.

2010年戈登生物学转录后基因调控研究会议将于2010年7月18日至7月23日举行；

• 批准号: 0964990
• 负责人: Lynne Maquat
• 金额: $ 0.7万
• 依托单位: Gordon Research Conferences
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0964990&HistoricalAwards=false
• 关键词: 2010; Gordon; Research; Conference; Biology

The Gordon Research Conference (GRC) on "The Biology of Post-Transcriptional Gene Regulation" will be held at Salve Regina University in Newport, Rhode Island, from July 18th to July 23rd, 2010. This meeting is the fourth in a GRC series that has been held every other year since 2004. The goal of this series is the elucidation of the fundamental mechanisms and regulation of RNA biogenesis. The emphasis is on post-transcriptional transactions involving the generation and metabolism of mRNA, but this extends to transcriptional coupling, and to factors involved in translation and its control, including tRNA and non-coding (e.g., micro) RNAs. Representing key areas of post-transcriptional gene regulation, the speakers will include a number of internationally known experts in this field, along with more junior speakers chosen on the basis of the content of their submitted abstracts. Approximately 150 participants are expected for the five-day meeting. The program will consist of nine morning or evening sessions that broadly address cutting-edge issues in the areas of coupling between transcription and RNA processing; genomics and evolution of RNA-processing signals and factors; RNA splicing catalysis, fidelity, and regulation; RNA turnover, including nonsense-mediated mRNA decay; RNA transport and localization; non-coding RNA; translational control; and RNA-protein interactions. In addition, four small poster sessions will enable all participants to contribute to, and learn about, these topics. Free early-afternoon and late-evening periods in the relatively isolated summer setting of Salve Regina University should stimulate productive, informal discussions among established and more junior investigators, postdoctoral trainees, and graduate students from the U.S. and abroad. This Gordon Research Conference has a unique format that brings together sets of researchers - graduate students, post-doctoral fellows, principal investigators at all career stages, grant administrators, scientists from the pharmaceutical and publishing industries who, despite converging interests, have only infrequent opportunities to meet as a group. The resulting intellectual cross-fertilization will help define critical areas and thus help propel this field forward. Understanding the basic mechanisms of post-transcriptional gene regulation is essential for a full understanding of the organization, function, and evolution of genomes. Speakers for this conference include 17 females and five underrepresented minorities. The selection of attendees from the pool of applicants will employ the principles of affirmative action with respect to minorities, women, and junior scientists. Funds from the National Science Foundation will support the attendance of young investigators working in U.S. laboratories, including graduate students, post-doctoral fellows, and beginning principal investigators.

戈登研究会议(GRC)“转录后基因调控的生物学”将于2010年7月18日至7月23日在罗德岛州纽波特的Salve Regina大学举行。这次会议是自2004年以来每隔一年举行一次的GRC系列会议中的第四次。本系列的目标是阐明RNA生物发生的基本机制和调控。重点是涉及mRNA的产生和代谢的转录后交易，但这延伸到转录耦合，以及参与翻译及其控制的因素，包括tRNA和非编码(例如，微)RNA。演讲者代表转录后基因调控的关键领域，将包括该领域的一些国际知名专家，以及根据其提交的摘要内容挑选的较初级演讲者。预计将有大约150人参加为期五天的会议。该计划将包括九个上午或晚上的会议，广泛讨论以下领域的前沿问题：转录和RNA加工之间的耦合；基因组学和RNA加工信号和因子的进化；RNA剪接催化、保真度和调节；RNA周转，包括无意义介导的mRNA衰变；RNA运输和定位；非编码RNA；翻译控制；以及RNA与蛋白质的相互作用。此外，四个小海报会议将使所有参与者能够为这些主题作出贡献，并了解这些主题。在Salve Regina大学相对与世隔绝的夏季环境中，自由的下午早些时候和晚些时候的时间应该会刺激成熟的和更初级的研究人员、博士后实习生和来自美国和海外的研究生之间进行富有成效的非正式讨论。这次戈登研究会议有一种独特的形式，汇集了多组研究人员--研究生、博士后研究员、所有职业阶段的首席研究员、拨款管理人员、制药和出版行业的科学家，尽管他们的兴趣一致，但作为一个群体，他们很少有机会见面。由此产生的智力交叉将有助于确定关键领域，从而有助于推动这一领域向前发展。了解转录后基因调控的基本机制对于全面了解基因组的组织、功能和进化是至关重要的。这次会议的发言人包括17名女性和5名代表不足的少数族裔。从申请者中挑选与会者将采用针对少数群体、妇女和初级科学家的平权行动原则。来自国家科学基金会的资金将支持在美国实验室工作的年轻研究人员的出席，包括研究生、博士后研究员和初级首席研究人员。