Conference: Post-Transcriptional Control of Gene Expression: Effectors of mRNA Decay to be held July 6-11, 2002 in Tucson, Arizona

会议：基因表达的转录后控制：mRNA 衰变效应器将于 2002 年 7 月 6 日至 11 日在亚利桑那州图森举行

• 批准号: 0129912
• 负责人: Lynne Maquat
• 金额: $ 0.51万
• 依托单位: Federation of Amer Societies For Exper Biology
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-04-01 至 2003-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0129912&HistoricalAwards=false
• 关键词: Conference; Post; Transcriptional; Control; Gene

The Federation of American Societies of Experimental Biology (FASEB) conference entitled "Post-Transcriptional Control of Gene Expression: Effectors of mRNA Decay" will be held July 6-11, 2002 in Tucson, Arizona. The objective of this conference is to provide an opportunity for the cross-fertilization of ideas between workers studying mRNA decay in prokaryotes and eukaryotes. mRNA decay plays a major role in determining the level at which genes are expressed. Therefore, understanding the mechanisms of mRNA degradation becomes very important to understanding how genes are regulated. Among the topics planned for this conference are: (1) A keynote overview of mRNA decay at the start of the conference by Dr. Roy Parker (University of Arizona). (2) Multicomponent bacterial nucleases. (3) Multicomponent eukaroytic nucleases. (4) How mRNA transport and localization affect mRNA decay. (5) How translational accuracy affects mRNA decay, including how the premature termination of translation elicits mRNA decay. (6) Cis-acting mRNA sequences and their associated trans-acting factors that affect mRNA decay. (7) RNA as a tool and target for drug design.

美国实验生物学学会联合会（FASEB）将于2002年7月6日至11日在亚利桑那州图森市举行题为“基因表达的转录后控制：mRNA衰变的效应”的会议。 本次会议的目的是为研究原核生物和真核生物中mRNA衰变的工作者提供一个思想交流的机会。 mRNA衰变在决定基因表达水平方面起着重要作用。 因此，了解mRNA降解的机制对于了解基因是如何调控的变得非常重要。 本次会议计划的主题包括：（1）Roy帕克博士（亚利桑那大学）在会议开始时对mRNA衰变的主题概述。(2)多组分细菌核酸酶。(3)多组分真核溶解核酸酶。(4)mRNA的运输和定位如何影响mRNA的衰变。(5)翻译准确性如何影响mRNA衰变，包括翻译的过早终止如何加速mRNA衰变。(6)顺式作用mRNA序列及其相关的影响mRNA衰变的反式作用因子。(7)RNA作为药物设计的工具和靶标。