Self-Assembled Organic Nanotubes from Cyclic Ureas

南卡罗来纳大学的Linda Shimizu教授在化学系大分子、超分子和纳米化学计划的支持下开发了双尿素大环，这种大环可预测地组装成直径在~1 nm或更小的均匀通道的柱状结构。这个方案开发了新的自组装大环，探索了利用这些材料来吸附活性分子，并研究了在这个有限的空间内进行反应的效果。对小空间中控制分子反应的因素的基础了解可能会导致使用更少活性和更安全的试剂的有机合成的新方法。这样的综合改进将是环保和经济的。本研究为本科生和研究生提供有机化学和材料化学方面的培训。此外，该奖项还支持化学示范计划的继续，该计划将化学家带到南卡罗来纳州的K-12教室，展示科学方法并培养人们对化学和自然科学的兴趣。

Professor Linda Shimizu of the University of South Carolina is supported by the Macromolecular, Supramolecular and Nanochemistry Program of the Division of Chemistry to develop bis-urea macrocycles that predictably assemble into columnar structures with homogeneous channels with diameters of ~ 1 nm or less. This proposal develops new self-assembling macrocycles, explores the use of these materials to absorb reactive molecules, and investigates the effects of carrying out reactions within this confined space.Fundamental understanding of the factors that govern the reaction of molecules in small spaces could lead to new methods for organic synthesis that utilize less reactive and safer reagents. Such synthetic improvements would be environmentally friendly and economical. This research provides training for undergraduates and graduate students in organic and materials chemistry. In addition, this award supports the continuation of a chemical demonstration program that brings chemists into South Carolina K-12 classrooms to showcase the scientific method and foster interest in chemistry and the natural sciences.