Self-Assembled Organic Nanotubes from Cyclic Ureas

南卡罗来纳州大学的琳达清水教授得到化学系大分子、超分子和纳米化学项目的支持，开发可预测地组装成具有直径约1 nm或更小的均匀通道的柱状结构的双脲大环。该提案开发了新的自组装大环，探索了使用这些材料吸收活性分子，并研究了在这种有限空间内进行反应的效果。对控制小空间中分子反应的因素的基本理解可能会导致使用反应性较低和更安全的试剂进行有机合成的新方法。 这种合成改进将是环境友好和经济的。 本研究为有机化学和材料化学的本科生和研究生提供了培训。 此外，该奖项还支持继续开展化学演示计划，将化学家带入南卡罗来纳州K-12教室，展示科学方法，培养对化学和自然科学的兴趣。

Professor Linda Shimizu of the University of South Carolina is supported by the Macromolecular, Supramolecular and Nanochemistry Program of the Division of Chemistry to develop bis-urea macrocycles that predictably assemble into columnar structures with homogeneous channels with diameters of ~ 1 nm or less. This proposal develops new self-assembling macrocycles, explores the use of these materials to absorb reactive molecules, and investigates the effects of carrying out reactions within this confined space.Fundamental understanding of the factors that govern the reaction of molecules in small spaces could lead to new methods for organic synthesis that utilize less reactive and safer reagents. Such synthetic improvements would be environmentally friendly and economical. This research provides training for undergraduates and graduate students in organic and materials chemistry. In addition, this award supports the continuation of a chemical demonstration program that brings chemists into South Carolina K-12 classrooms to showcase the scientific method and foster interest in chemistry and the natural sciences.