POWRE: Self-Assembling Cyclic Ureas

该研究的重点是通过大环单体的酰胺和羰基之间的氢键相互作用形成的中空管状纳米结构的合成和表征，每个大环单体包含两个脲单元连接形成甜甜圈形状的构建块。 （-YHNCONH-）2中的Y接头单元含有芳环以保持环状单体平面，并且可以选择以提供各种管尺寸和疏水性。 基于已知的分子结构，甜甜圈之间的重复距离预计为4.61埃。 预计在溶液中自组装的管将通过质子和碳NMR，STM和X射线衍射进行表征。 有了这个POWRE奖，化学部支持琳达S。Shimizu博士在南卡罗来纳州哥伦比亚的南卡罗来纳州大学化学和生物化学系工作。 拟议的研究将探索控制分子尺寸的中空有机管的合成和表征，这些中空有机管有望用作离子和小分子传输装置、传感器和催化剂。

The research is focused on the synthesis and characterization of hollow tubular nano-structures formed by hydrogen bonding interactions between amide and carbonyl groups of macrocyclic monomers, each of which contains two urea units linked to form a donut shaped building block. The Y linker units in (-YHNCONH-)2 contain aromatic rings to keep the cyclic monomers planar, and can be chosen to provide a variety of tube dimensions and hydrophobicities. Based on known molecular structures, the repeat distance between donuts is expected to be 4.61 Angstroms. The tubes, which are expected to self-assemble in solution, will be characterized by proton and carbon NMR, STM, and x-ray diffraction. With this POWRE award the Chemistry Division supports the work of Linda S. Shimizu in the Department of Chemistry and Biochemistry at the University of South Carolina in Columbia, SC. The proposed research will explore the synthesis and characterization of hollow organic tubes of controlled molecular dimensions which are expected to find uses as ion and small molecule transport devices, sensors and catalysts.