SBIR Phase I: Development of a commercial two-dimensional infrared (2D IR) spectrometer for characterization of chemical systems

这项小型企业创新研究（SBIR）第一阶段项目旨在证明商业上可行的二维红外光谱仪的可行性。二维红外光谱是一种新兴的研究和分析工具。在过去的10年里，大约有40个学术实验室开始使用这项技术来研究从太阳能电池材料中的电子转移到蛋白质折叠的各种问题。该提案的目的是将激光技术的进步与中红外脉冲整形技术的进步结合起来，构建一个强大、自动化、技术上比现有技术更先进的二维红外光谱仪。这个项目的广泛影响/商业潜力将是三倍的。首先，与其他技术相比，由于2D红外光谱具有独特的时间和结构灵敏度，因此它将加强对广泛学科的科学理解。其次，我们的结果将在学术和贸易会议上传播，这将影响更广泛的科学界和工业界。第三，这一文书在本提案中的商业影响将是巨大的。红外光谱仪在世界各地的学术和工业研究实验室中经常使用。商用2D红外光谱仪将比目前的红外光谱仪实现更高的灵敏度和更准确的分析测量，从而有助于制药代理商，储能材料和许多其他产品的进步。

This Small Business Innovation Research (SBIR) Phase I project aims to demonstrate the feasibility of a commercially viable two-dimensional infrared (2D IR) spectrometer. 2D IR spectroscopy is an emerging research and analytical tool. Over the last 10 years since it was first invented, about 40 academic laboratories have begun using the technique to study problems ranging from electron transfer in solar-cell materials to protein folding. The aim of this proposal is to combine advances in laser technology with advances in mid-IR pulse shaping to construct a 2D IR spectrometer that is robust, automated, and technologically more advanced than currently existing technologies.The broader impact/commercial potential of this project will be three-fold. First, it will enhance scientific understanding across a wide range of disciplines because of the unique time and structure sensitivity of 2D IR spectroscopy as compared to other techniques. Second, our results will be disseminated at academic and trade conferences, which will impact the broader scientific and industrial communities. Third, the commercial impact of this instrument in this proposal will be substantial. Infrared spectrometers are used routinely in academic and industrial research labs throughout the world. A commercial 2D IR spectrometer would enable higher sensitivities and more accurate analytical measurements than possible with current infrared spectrometers, thereby contributing to advances in pharmaceutical agents, energy storage materials, and many other products.