BioFEL Workshop at Lawrence Berekeley Laboratory on January 18-21, 2011.
BioFEL Workshop at Lawrence Berekeley Laboratory on January 18-21, 2011.
批准号:
1101357
负责人:
John Spence
金额:
$0.5万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2011
资助国家:
美国
项目状态:
已结题
起止时间:
2011-03-01 至 2012-02-29
中文摘要
该奖项部分资助了劳伦斯伯克利实验室关于自由电子激光在生物科学中的使用的研讨会。讲习班将有大约120人参加,将于2011年1月举行。研讨会将探索最近发明的硬X射线激光为生物学提供的令人兴奋的可能性。PIS将汇集生物物理、结构生物学、生物化学、加速器物理和衍射物理领域的领先者,审查正在建设的许多自由电子激光器(FEL)的独特能力提供的研究机会。课程内容包括泵浦-探测蛋白质动力学、室温下的原位化学快照衍射、蛋白质纳米晶体的生长和合成、细胞和病毒的单次激发成像、快速从头算起伏SAXS、重建和定相算法、探测器、源和蛋白质束注入器。一个由资深生物学家组成的小组将概述结构生物学的需求,并为该领域的发展提出建议。研讨会由劳伦斯·利弗莫尔国家实验室、劳伦斯·伯克利国家实验室、亚利桑那州立大学SLAC国家加速器实验室和加州大学戴维斯分校生物光子学科学与技术中心共同资助。
英文摘要
This award partially supports a workshop at Lawrence Berkeley Laboratory on the use of the Free Electron Laser in the biological sciences. The workshop will have approximately 120 attendees, and it will be held in January 2011. The workshop will explore the exciting possibilities which the recent invention of the hard Xray laser offers for biology. The PIs will bring together leaders in the fields of biophysics, structural biology, biochemistry, accelerator physics, and diffraction physics to review the research opportunities which the unique capabilities of the many Free Electron Lasers (FELs) which are being constructed provide. Topics covered will include pump-probe protein dynamics, in-situ chemical snapshot diffraction at room temperature, protein nanocrystal growth and synthesis, single-shot imaging of cells and viruses, fast ab-initio fluctuation SAXS, reconstruction and phasing algorithms, detectors, sources and protein-beam injectors. A panel of senior biologists will outline the needs of structural biology, and suggest lines of development for this field. The workshop is co-funded by Lawrence Livermore National Laboratory, Lawrence Berkeley National Laboratory, SLAC National Accelerator Laboratory, Arizona State University, and the Center for Biophotonics Science and Technology at University of California at Davis.
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会议论文
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依托单位:
海外基金