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Modelling of the Environmental Fate and Effects of Veterinary Medicines in Soil under Field Conditions

野外条件下土壤环境归趋和兽药影响的建模

基本信息

批准号：
201600593
负责人：
Professor Dr. Michael Matthies
金额：
--
依托单位：
Institut für Umweltsystemforschung
依托单位国家：
德国
项目类别：
Research Units
财政年份：
2011
资助国家：
德国
起止时间：
2010-12-31 至 2014-12-31
项目状态：
已结题

来源：
https://gepris.dfg.de/gepris/projekt/201600593?language=en
关键词：
Modelling Environmental Fate Effects Veterinary

项目摘要

In the 2nd phase, we simulated fate and effects of SDZ and its main metabolites under consideration of field temperature and moisture conditions and could explain a large part of the observed variability by temperature and instantaneously moisture effects. For these simulations, the established model structure and kinetic rate constants as determined from micro- and mesocosm experiments under constant conditions were used. However, implicit uncertainties of relevant processes prevent a priori predictions of SDZ fate in manured soil and resulting effects on nitrification and resistance gene selection. Both the release of SDZ and 4-OH-SDZ from the residual fraction and biotic endpoints such as abundance and activity of ammonium oxidizing archaea seems to be influenced by soil moisture conditions in a not yet well understood manner. In the 3rd phase of our Research Unit we will test the validity of the coupled fate and effect model under field conditions. The influence of variable moisture and temperature on transformation and sequestration processes of SDZ as well as on resulting effects on nitrification and resistance gene selection will be analysed based on field and greenhouse experiments. Fate and effect processes will be simulated under drying and re-wetting cycles and compared to static moisture conditions. Most sensitive processes and parameters will be identified and uncertainties of predictions quantified by Monte-Carlo analysis.

在第二阶段，我们模拟了SDZ及其主要代谢产物的命运和影响，考虑到现场温度和湿度条件下，可以解释很大一部分的温度和瞬时湿度效应所观察到的变异。对于这些模拟，所建立的模型结构和动力学速率常数，确定从微观和围隔实验在恒定的条件下使用。然而，隐含的不确定性，相关的过程，防止先验预测SDZ的命运施肥土壤和硝化和抗性基因选择的影响。SDZ和4-OH-SDZ从残留部分和生物终点（如铵氧化古菌的丰度和活性）的释放似乎受到土壤水分条件的影响，但尚未得到很好的理解。在第三阶段，我们的研究单位，我们将测试耦合的归宿和影响模型在现场条件下的有效性。根据田间和温室试验，分析了水分和温度变化对SDZ转化和封存过程的影响以及对硝化和抗性基因选择的影响。将在干燥和再润湿循环下模拟最终结果和影响过程，并与静态水分条件进行比较。将确定最敏感的过程和参数，并通过蒙特-卡罗分析量化预测的不确定性。