BRIGE: Nanocrystal Probes for Tip-Enhanced Raman Spectroscopy

智力优势：纳米级金属尖端的行为就像光学天线，以促进散射光的近场放大，并正在探索作为高分辨率的扫描探针，用于超灵敏的振动光谱。为了从每个探针获得最高的信号增益，金属尖端必须设计成具有高度调节的尺寸和形状。目前的制造方法产生具有一系列纳米级特征的尖端，这些纳米级特征难以表征并且在使用时遭受机械和热损伤。BRIGE项目的研究目标是通过将胶体金属纳米晶体组装到原子力显微镜针尖上来制造金属针尖。该提案将评估纳米陶瓷为基础的提示作为一个功能的陶瓷形状，大小和组装几何光学响应。纳米晶体组件将被设计成实现特定的近场电磁特性，包括可调谐等离子体激元激发波长，多个纳米晶体之间的电磁耦合，以及最佳的倏逝场衰减长度。最后，该项目将寻求将这些拉曼组件与扫描探针仪器相结合，并展示尖端增强的拉曼光谱用于化学鉴定、检测和绘图等应用。更广泛的影响：拟议的研究将导致开发强大的，定制的，和超灵敏的纳米级探针尖端的尖端增强拉曼光谱和其他近场光学测量。一种能够将定量化学分析与超出衍射极限的空间分辨率配对的光学技术将在需要表面表征的广泛领域产生巨大影响，包括：化学传感和分子识别，多相催化，纳米结构表征，生物材料开发和基础生命科学研究。该研究项目将通过将研究与指导，教育和社会推广相结合来产生广泛的影响。该提案的研究成果将被介绍给加州大学圣地亚哥分校纳米工程课程的本科生，作为纳米工程基础研究如何推动技术创新的一个例子。将与社区组织合作，促进大学前一级的纳米科学教育，特别注意通过纳入代表性不足的少数民族和妇女来扩大参与。此外，拟议的努力包括开发在线维基，以便在纳米材料界之外传播研究成果。这些不同的教育组成部分将被设计为吸引各级教育的工程师，鼓励与他们的同龄人，导师和社区进行开放的科学讨论。

Intellectual Merit: Nanoscale metal tips behave like optical antenna to facilitate near-field amplification of scattered light and are being explored as high-resolution scanning probes for ultrasensitive vibrational spectroscopy. To obtain the highest signal gain from each probe, the metal tip must be designed with highly regulated size and shape. Current fabrication methods produce tips with a range of nanoscopic features that are difficult to characterize and suffer from both mechanical and thermal damage upon use. The research objective of this BRIGE project is to fabricate metal tips by assembling colloidal metal nanocrystals onto an atomic force microscope tip. This proposal will evaluate the optical response of nanocrystal-based tips as a function of nanocrystal shape, size, and assembly geometry. Nanocrystal assemblies will be engineered to achieve specific near-field electromagnetic properties, including tunable plasmon excitation wavelengths, electromagnetic coupling between multiple nanocrystals, and optimal evanescent field decay lengths. Finally, this project will seek to integrate these nanocrystal assemblies with scanning probe instrumentation and to demonstrate tip-enhanced Raman spectroscopy for applications such as chemical identification, detection, and mapping. Broader Impacts: The proposed research will lead to the development of robust, tailored, and ultrasensitive nanoscale probe tips for tip-enhanced Raman spectroscopy and other near-field optical measurements. An optical technique that is able to pair quantitative chemical analysis with spatial resolution beyond the diffraction limit would have a tremendous impact in a broad range of fields that require surface characterization, including: chemical sensing and molecular identification, heterogeneous catalysis, nanostructure characterization, biomaterials development, and basic life sciences research. This research project will make broad impacts by integrating research with mentoring, education, and social outreach. The research outcomes of this proposal will be introduced to undergraduates within the NanoEngineering curriculum at UC San Diego as an example of how basic research in nanoengineering can drive technological innovation. Work will be conducted with community-based organizations to promote nanoscience education at the precollege level, with particular attention given toward broadening participation through the inclusion of underrepresented minorities and women. In addition, the proposed efforts include the development of online wikis for the dissemination of research results beyond the nanomaterials community. These different educational components will be designed to engage engineers at all levels of education, encouraging open lines of scientific discussion with their peers, mentors, and community.