CSR-CSI: Software Environment for Real-Time Non-Rigid Registration using Commodity and Grid Computing

CSR-CSI：使用商品和网格计算进行实时非刚性注册的软件环境

• 批准号: 1136536
• 负责人: Nikos Chrisochoides
• 金额: $ 11.41万
• 依托单位: Old Dominion University Research Foundation
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1136536&HistoricalAwards=false
• 关键词: CSR; CSI; Software; Environment; Real

In this project we will focus on four important aspects (requirements)of an end-to-end software environment for performing multiple parallelnon-rigid registrations over the Grid. Our application is Image GuidedNeurosurgery (IGNS). IGNS is an important tool for neurosurgicalresection which is a common therapeutic intervention in the treatmentof malignant brain tumors.The four requirements we will study in this project are: (1) thehigh-performance of the parallel and distributed non-rigidregistration code by dynamically balancing the processors work-load,(2) the ease-of-use from medical doctors (radiologist) of aweb-service by developing a Graphical User Interface (GUI) for clientsof our web-service (3) the portability of the code to run from asingle high-end workstation to more than one clusters of workstationswithin the local and wide area networks available to researchhospitals and medical centers, (4) the reliability by guaranteeingthat part of the system will complete the computations for the imageregistration and by making sure we meet the time constrains byacquiring and re-configuring the system at runtime to compensate forlost (faulty) computing resources.The end-product will be a prototype of an IGNS web-service. However,this project will have broader impact to image guided therapy becausethe same framework (but different modalities and finite elementapproximation models) can be used in prostate biopsy and treatment,and liver cryotherapy.

在这个项目中，我们将重点关注在网格上执行多个并行非刚性注册的端到端软件环境的四个重要方面(需求)。我们的应用是图像引导神经外科(IGNS)。IGNS是神经外科手术的重要工具，也是恶性脑肿瘤治疗中常用的治疗手段。我们将研究的四个要求是：(1)通过动态平衡处理器的工作负载来实现并行和分布式非刚性注册码的高性能，(2)医生(放射科医生)通过为我们的网络服务的客户端开发图形用户界面(GUI)而易于使用网络服务(3)代码可从单个高端工作站运行到研究医院和医疗中心可用的局域网和广域网内的多个工作站集群，(4)可靠性，通过保证系统的一部分将完成图像注册的计算，并通过在运行时获取并重新配置系统以补偿丢失的(错误的)计算资源来确保满足时间约束。最终产品将是IGNS网络服务的原型。然而，该项目将对图像引导治疗产生更广泛的影响，因为相同的框架(但不同的模式和有限元近似模型)可以用于前列腺活检和治疗，以及肝脏冷冻治疗。