Crystallization and cooperativity in dynamic supramolecular polymers (A03)

动态超分子聚合物的结晶和协同作用（A03）

• 批准号: 203191613
• 金额: --
• 依托单位: Arbeitsbereich Technische Chemie und Makromolekulare Chemie
• 依托单位国家: 德国
• 项目类别: CRC/Transregios
• 财政年份: 2011
• 资助国家: 德国
• 起止时间: 2010-12-31 至 2022-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/203191613?language=en
• 关键词: Crystallization; cooperativity; dynamic; supramolecular; polymers

We investigate the structure formation of biomimetic synthetic macromolecules from either the melt state or the solution state, aiming to understand folding and assembly principles between different segments of a polymer molecule. In the new funding period complex, artificial biomimetic elements will be synthesized by repetitive placement within a synthetic polymer chain, able to adopt specific conformations, dynamically changing from folded (e.g. α-helix, β- fold) to unfolded conformations. The proposed synthetic macromolecules are structurally placed between biological macromolecules and purely synthetic molecules, allowing to understand basic structure-formation and nucleation processes of partially unfolded macromolecules.

我们研究了仿生合成大分子的结构形成，无论是从熔融状态还是溶液状态，旨在了解聚合物分子的不同片段之间的折叠和组装原理。在新的资助期内，人工仿生元件将通过在合成聚合物链内重复放置来合成，能够采用特定的构象，从折叠（例如α-螺旋，β-折叠）动态变化为展开构象。所提出的合成大分子在结构上介于生物大分子和纯合成分子之间，允许理解部分未折叠大分子的基本结构形成和成核过程。