CAREER: Exploring the mechanistic roles of NF-Y transcription factors in photoperiod-dependent flowering

职业:探索 NF-Y 转录因子在光周期依赖性开花中的机制作用

基本信息

  • 批准号:
    1149822
  • 负责人:
  • 金额:
    $ 93.07万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Continuing Grant
  • 财政年份:
    2012
  • 资助国家:
    美国
  • 起止时间:
    2012-03-01 至 2018-12-31
  • 项目状态:
    已结题

项目摘要

The timing of flowering is especially important in plant development because it directly impacts reproductive success. For example, flowering at the wrong time could mean that important pollinators are not present or that fragile embryos will be subjected to freezing temperatures. Thus, plants have complex and highly specific mechanisms to harmonize flowering with the natural ecosystems in which they evolved. Understanding flowering time has further important implications in agricultural settings, as flowering time can have profound effects on the overall production of commercially valuable vegetative organs, fruits, and seeds. To properly time flowering, many plants have an internal clock that monitors day length (photoperiod) and seasonally activates genes that drive the transition from vegetative growth to reproductive growth. In particular, activation of the floral integrator gene FLOWERING LOCUS T (FT) is an essential early step in the photoperiod-regulated transition to flowering. This project uses a combination of genetic and biochemical approaches to specifically investigate how regulatory proteins called NUCLEAR FACTOR Y (NF-Y) mechanistically control FT expression to initiate flowering. In addition to potentially impacting agricultural production and our collective understanding of natural ecosystems, this project will train undergraduate and graduate students in both the research and classroom laboratories. Elements of the research aims will be incorporated into an upper division Plant Physiology course. Additionally, molecular plant biology forums will be initiated as part of an effort to improve collaborative interactions among Oklahoma researchers. All discoveries and resources developed from this funding will be made freely publicly available through a combination of peer-reviewed publications, distribution to public stock centers/data repositories, and direct distribution of materials.
开花的时间在植物发育中特别重要,因为它直接影响生殖成功。例如,在错误的时间开花可能意味着重要的授粉者不存在,或者脆弱的胚胎将受到冷冻温度的影响。因此,植物具有复杂和高度特异性的机制来协调开花与它们进化的自然生态系统。了解开花时间在农业环境中具有进一步的重要意义,因为开花时间可以对具有商业价值的营养器官,果实和种子的整体生产产生深远的影响。为了正确安排开花时间,许多植物都有一个内部时钟来监测日照长度(光周期)并季节性激活驱动从营养生长向生殖生长过渡的基因。特别是,花整合基因FLOWERLOCUS T(FT)的激活是光周期调节的开花过渡的重要早期步骤。该项目使用遗传和生物化学方法相结合,专门研究称为核因子Y(NF-Y)的调节蛋白如何机械地控制FT表达以启动开花。除了可能影响农业生产和我们对自然生态系统的集体理解外,该项目还将在研究和课堂实验室培训本科生和研究生。研究目标的要素将被纳入高等植物生理学课程。此外,分子植物生物学论坛将作为努力改善俄克拉荷马州研究人员之间合作互动的一部分。从这笔资金中开发的所有发现和资源将通过同行评审的出版物,分发到公共库存中心/数据存储库以及直接分发材料的组合免费公开。

项目成果

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Ben Holt III其他文献

Ben Holt III的其他文献

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{{ truncateString('Ben Holt III', 18)}}的其他基金

Functional analysis of multi-gene complexes regulating photoperiod-dependent flowering time
调控光周期依赖性开花时间的多基因复合体的功能分析
  • 批准号:
    0920258
  • 财政年份:
    2009
  • 资助金额:
    $ 93.07万
  • 项目类别:
    Standard Grant

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