REU Site: Engineering Tools for Decision Support in Systems Medicine

REU 网站：系统医学决策支持工程工具

• 批准号: 1156899
• 负责人: Robert Parker
• 金额: $ 35.77万
• 依托单位: University of Pittsburgh
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-03-01 至 2017-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1156899&HistoricalAwards=false
• 关键词: REU; Site; Engineering; Tools; Decision

Intellectual MeritThe primary objective of this new three-year REU site program at the University of Pittsburgh is to expose 9 undergraduate students per year to research in the emerging field of systems medicine. Systems medicine problems are characterized by complex interacting systems requiring multidisciplinary knowledge to formulate and solve. The intellectual merit of this REU proposal derives from the emergence of this field and the need for experts with the knowledge and motivation to address constrained real-world problems where mathematical models can provide hypothesis-generating and in validating predictions. Furthermore, systems medicine is underserved by existing REU sites, in comparison to other areas of biomedical research, and this site would expand the existing REU portfolio while educating students who could serve as the next generation of leaders in the field. The necessity of coupling modeling and systems analysis approaches to experimental data; thereby yielding a predictive model upon validation is a prerequisite to solving clinically-relevant systems medicine problems. Through a series of mentored research and teaching experiences, REU students will take the first step on the path to becoming the next generation of experts in the field of systems medicine.Broader ImpactsThe PI will actively recruit underrepresented undergraduates to participate in interdisciplinary research and to advance the abilities of all students in the program with respect to communication, teamwork, and professional skills. Through existing relationships, and the development of new ones with minority, female, or primarily undergraduate institutions, the program will provide a pathway to graduate education for populations that are traditionally underrepresented at the engineering (and STEM) post-graduate level by fostering the ability to independently and collaboratively investigate systems medicine research problems. One path of dissemination is to design simulations for use in K-12 education; through partnering with the CTSI "Mobile Lab" to bring computational experiments to K-12 students in an effort to stimulate the desire of these students to pursue STEM subjects at the baccalaureate level.

智力价值匹兹堡大学这个新的为期三年的REU现场项目的主要目标是每年让9名本科生接触新兴的系统医学领域的研究。系统医学问题的特点是复杂的相互作用的系统，需要多学科的知识来制定和解决。REU建议的智力价值来自这一领域的出现，以及需要有知识和动机的专家来解决受限制的现实世界问题，在这些问题中，数学模型可以提供假设生成和验证预测。此外，与生物医学研究的其他领域相比，现有的REU网站提供的系统医学服务不足，该网站将扩大现有的REU产品组合，同时培养可能成为该领域下一代领导者的学生。对实验数据进行耦合建模和系统分析的必要性；从而在验证后产生预测模型是解决与临床相关的系统医学问题的先决条件。通过一系列有指导的研究和教学经验，REU的学生将在成为系统医学领域的下一代专家的道路上迈出第一步。广泛的影响PI将积极招募未被充分代表的本科生参与跨学科研究，并提高该项目所有学生在沟通、团队合作和专业技能方面的能力。通过现有的关系，以及与少数族裔、女性或主要是本科院校的新关系的发展，该项目将通过培养独立和合作研究系统医学研究问题的能力，为传统上在工程学(和STEM)研究生水平上代表性不足的人群提供一条研究生教育的途径。一种传播途径是设计用于K-12教育的模拟；通过与CTSI“移动实验室”合作，将计算实验带给K-12学生，努力激发这些学生攻读学士学位水平的STEM科目的愿望。