Collaborative Research: New Ratiometric Fluorescent Indicators for Copper

在化学测量和成像计划的支持下，以及刺激竞争性研究的实验计划的共同资助下，教授。新罕布什尔大学的Rudolf Seitz和Roy Planalp与康涅狄格大学的Shawn Burdette教授合作，正在开发和表征一种制备基于共聚物的金属离子比例荧光指示剂的新方法。该方法将络合作用与荧光分离开来，从而可以为Cu（II）、Pb（II）、Fe（III）等重要金属离子制备比率指示剂，这些金属离子通常会猝灭荧光。该项目将提供一种新的方法来测量市政水域中有毒金属的水平，并将对公共安全产生迅速和积极的影响，因为它与环境系统公司建立了关系，该公司是一家妇女商业企业认证的公司，能够迅速发展实验室研究以供实际应用。该项目将涉及包括高中、本科、研究生和博士后在内的许多层次的参与者和受训者，并将涉及代表性不足的群体和妇女。新学生将被指派一名高级研究生或博士后导师，与项目负责人分担指导职责。

With support from the Chemical Measurement and Imaging Program, and co-funding from the Experimental Program to Stimulate Competitive Research, Profs. Rudolf Seitz and Roy Planalp from the University of New Hampshire, in collaboration with Prof. Shawn Burdette from the University of Connecticut, are developing and characterizing a new approach to preparing co-polymer based ratiometric fluorimetric indicators for metal ions. The approach separates complexation from fluorescence, thereby allowing preparation of ratiometric indicators for important metal ions like Cu(II), Pb(II), Fe(III), etc., which normally quench fluorescence. This project will provide a new approach to measuring levels of toxic metals in municipal waters and will have a rapid and positive impact on public safety because of an established relationship with Envirosystems, Inc., a Womens Business Enterprise-certified company that can rapidly develop laboratory research for practical applications. The project will involve participants and trainees at many levels including high school, undergraduate, graduate, and postdoctoral, and will involve underrepresented groups and women. New students beginning on this project will be assigned a senior graduate student or postdoctoral mentor, who will share mentoring duties with the PI.