The role of human single-stranded binding protein (hSSB1) in DNA damage repair and tumorogenesis.

癌症是全世界疾病相关死亡的主要原因，2007年占所有死亡人数的13%以上。2005年，澳大利亚约有3.8万人死于癌症。癌症是由于单个细胞失去了其遗传信息的重要部分，这导致细胞失去了正常的程序，并开始了快速生长和繁殖的过程。该研究项目旨在研究存在的机制，以防止单个细胞内遗传物质的初始损失。它的进一步目标是将这些发现转化为临床，为特定癌症的诊断和预后提供新的工具，并与主要制药公司建立联系，开发新的抗癌疗法。

Cancer is a leading cause of disease related death world wide, accounting for over 13% of all deaths in 2007. Approximately 38,000 people died in Australia from cancer in 2005. Cancer results from a single cell losing a vital part of its genetic information, this results in the cell losing its normal programming and initiates a process of rapid growth and multiplication. This research project aims to look at the mechanisms that exist to prevent this initial loss of genetic material within an individual cell. It further aims to translate theses discoveries into the clinic, providing new tools for diagnosis and prognosis of specific cancers and to establish links with major pharmaceutical companies to develop novel anticancer therapies.