MRI: Development of Visual and Neural Assessment Equipment

这项提案要求提供资金，以设计一种集成的、便携式的神经视觉评估系统，具有以下功能：1)具有用户友好的脚本语言的定制软件，为非工程师编写独立的、多个同时的左眼和右眼视觉刺激；2)根据视觉刺激同时进行眼睛运动和感官神经电活动量化；以及3)数据分析算法，以确定在识别神经和视觉缺陷方面敏感和特异的潜在生理测量或生物标记物。这一变革性的项目将使基础和临床研究科学家能够评估正常人群和受损人群的神经视觉功能。这一系统将被整合到PIS的本科生和研究生课程中。它将使每年约200名学生能够接受不断增长的生物医学工程领域所需的必要技能培训(例如，收集和分析生理数据)。它将用于每年向350多名4至12年级的学生介绍工程和数学的巡回演出。该项目的第一个应用将是评估生物标志物，以帮助诊断轻度创伤性脑损伤(MTBI)。

This proposal requests funding to design an integrated, portable neurovisual assessment system with the following capabilities: 1) custom software with user-friendly script language to program independent and multiple, simultaneous visual stimuli to the left and right eye for non-engineers, 2) simultaneous eye movement and sensory neuro-electrical activity quantification from visual stimuli, and 3) data analysis algorithms to determine potential physiological measurements or biomarkers that are sensitive and specific in identifying neurological and visual deficits. This transformative project will enable basic and clinical research scientists to assess neuro-visual functions in normal and impaired populations. This system will be integrated into the PIs' undergraduate and graduate courses. It will enable about 200 students annually to train in imperative skills needed in the growing Biomedical Engineering field (e.g. collect and analyze physiological data). It will be used for tours to introduce over 350 4th to 12th grade students annually to Engineering and Mathematics. The first application of this project will be to evaluate biomarkers to aid in the diagnosis of mild traumatic brain injury (mTBI).