MRI: Development of Visual and Neural Assessment Equipment

MRI：视觉和神经评估设备的开发

• 批准号: 1228254
• 负责人: Tara Alvarez
• 金额: $ 31.9万
• 依托单位: New Jersey Institute of Technology
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-01 至 2015-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1228254&HistoricalAwards=false
• 关键词: MRI; Development; Visual; Neural; Assessment

This proposal requests funding to design an integrated, portable neurovisual assessment system with the following capabilities: 1) custom software with user-friendly script language to program independent and multiple, simultaneous visual stimuli to the left and right eye for non-engineers, 2) simultaneous eye movement and sensory neuro-electrical activity quantification from visual stimuli, and 3) data analysis algorithms to determine potential physiological measurements or biomarkers that are sensitive and specific in identifying neurological and visual deficits. This transformative project will enable basic and clinical research scientists to assess neuro-visual functions in normal and impaired populations. This system will be integrated into the PIs' undergraduate and graduate courses. It will enable about 200 students annually to train in imperative skills needed in the growing Biomedical Engineering field (e.g. collect and analyze physiological data). It will be used for tours to introduce over 350 4th to 12th grade students annually to Engineering and Mathematics. The first application of this project will be to evaluate biomarkers to aid in the diagnosis of mild traumatic brain injury (mTBI).

该提案要求提供资金，以设计一个具有以下功能的综合便携式神经视觉评估系统：1）具有用户友好的脚本语言的定制软件，用于为非工程师的左眼和右眼编程独立的和多个同时的视觉刺激，2）来自视觉刺激的同时的眼睛运动和感觉神经电活动量化，和3）数据分析算法，以确定在识别神经和视觉缺陷方面敏感和特异的潜在生理测量或生物标记。这一变革性项目将使基础和临床研究科学家能够评估正常和受损人群的神经视觉功能。这一系统将被纳入PI的本科和研究生课程。它将使每年约200名学生在不断增长的生物医学工程领域所需的必要技能（例如收集和分析生理数据）的培训。它将用于图尔斯旅游介绍超过350 4至12年级的学生每年工程和数学。该项目的第一个应用将是评估生物标志物，以帮助诊断轻度创伤性脑损伤（mTBI）。