How motor action shapes emotion in the brain

运动动作如何塑造大脑中的情绪

• 批准号: 1257101
• 负责人: Daniel Casasanto
• 金额: $ 45.07万
• 依托单位: University of Chicago
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-15 至 2017-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1257101&HistoricalAwards=false
• 关键词: How; motor; action; shapes; emotion

_____________________________________________________________________________How is the diversity of the human experience reflected in the brain/mind? What is universal about the brain and mind, and what depends on the particulars of people's physical and social experiences? This project explores how the actions we perform with our bodies shape the neural processing of emotion. It asks whether right- and left-handers, who perform many actions differently, use correspondingly different areas of the brain to process one of the most basic components of human emotion: affective motivation (our predisposition to approach or avoid physical or social stimuli). The research team, led by Dr. Daniel Casasanto at the University of Chicago, will use a combination of behavioral tasks, brain imaging, and neural stimulation to test the hypothesis that the way people use their hands to perform approach-related actions and avoidance-related actions may determine how approach- and avoidance-related emotions are represented in the brain. There are important clinical implications of this basic research. FDA-approved neural therapies are currently in use to treat depression and anxiety disorders. These treatments are based on a one-size-fits-all model of the brain and mind. If the way we use our hands influences how emotions are distributed across the cerebral hemispheres, this may signal that treatments that are beneficial for right-handers may be detrimental for left-handers. Tailoring neural therapies to the specifics of patients' interactions with the world may be crucial for developing safe, effective treatments for common mental health issues.

__大脑和心灵的普遍性是什么？什么取决于人们的身体和社会经验的具体情况？这个项目探讨了我们如何用身体执行的动作塑造情绪的神经处理。它问的是，右撇子和左撇子在许多行为上的表现不同，他们是否使用相应的不同大脑区域来处理人类情感的最基本组成部分之一：情感动机（我们接近或避免身体或社会刺激的倾向）。 由芝加哥大学的丹尼尔·卡萨桑托博士领导的研究小组将使用行为任务、大脑成像和神经刺激的组合来测试一个假设，即人们使用手来执行与接近相关的动作和与回避相关的动作的方式可能决定了与接近和回避相关的情绪在大脑中的表现方式。这项基础研究具有重要的临床意义。FDA批准的神经疗法目前用于治疗抑郁症和焦虑症。这些治疗方法都是基于一种通用的大脑和思维模型。如果我们用手的方式影响了情绪在大脑半球的分布，这可能意味着对右撇子有益的治疗可能对左撇子有害。根据患者与世界互动的具体情况定制神经疗法，对于开发针对常见心理健康问题的安全有效的治疗方法至关重要。