Computational Studies of Protein Powder Hydration Phenomena

本PI将使用先进的分子模拟工具来研究和量化关键变量，如水化程度、碳水化合物辅料和温度对脱水和复水蛋白质的结构、稳定性和动力学的影响。该项目的成功成果将有助于开发高质量的治疗蛋白，并推动制药行业此类治疗药物的开发。

AbstractThis PI will use advanced molecular simulation tools to investigate and quantify the effects of key variables such as hydration level, carbohydrate excipients, and temperature on the structure, stability and dynamics of proteins undergoing dehydration and rehydration. The impact from the successful outcome of this project will help develop quality therapeutic proteins and advance the development such therapeutics for the pharmaceutical industry.