Planning Grant: I/UCRC for Design and Advanced Manufacturing of Integrated Microfluidics for Ubiquitious Diagnostics

规划补助金：I/UCRC 用于用于无处不在的诊断的集成微流体的设计和先进制造

• 批准号: 1266193
• 负责人: Abraham Lee
• 金额: $ 1.56万
• 依托单位: University of California-Irvine
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-02-15 至 2014-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1266193&HistoricalAwards=false
• 关键词: Planning; Grant; UCRC; Design; Advanced

1266193 University of California-Irvine (UC-I); Abraham Lee 1266195 University of Cincinnati; Ian Papautsky The proposed center will develop low-power, automated, self-contained, mass-produced micro-devices capable of multi-step biochemical assessments. University of California, Irvine (UC-I) and the University of Cincinnati (UCINN) are collaborating to establish the proposed center, with UCI as the lead institution. The goal of the proposed Center is to develop advanced manufacturing technologies for ubiquitious diagnostics and assessment of the environment, agriculture, and human health. The goals of this proposed Center will be achieved via three coordinated basic and applied research thrust areas: Manufacturable Processes and Materials, Sample Processing and Detection, and Integration and Control Systems. This Center would result in (a) advances that can be transferred to industrial stakeholders for product development, (b) technologies that feed into government laboratories for further application-specific development, and (c) the education and training of a cadre of specialized scientists and engineers skilled in low-cost manufacturable microfluidic biochip innovation. Broader impacts include competitive recruitment mechanisms and attractive cross-disciplinary collaborative graduate research opportunities to engage excellent students, including members of underrepresented groups. In addition to traditional and conferences, knowledge dissemination includes an open-source "microfluidic function library" containing design specifications for microfluidic circuits and interchangeable components organized by application and chip manufacturing processes. Scalable prototyping processes also will be disseminated to academia and industry, including established companies and entrepreneurs, with a goal to dramatically reduce the learning curve and streamline the idea-to-product process.

1266193加州大学欧文分校（UC-I）;亚伯拉罕李1266195辛辛那提大学;伊恩帕普茨基拟议的中心将开发低功耗，自动化，独立，大规模生产的微型设备，能够进行多步生化评估。加州大学欧文分校（UC-I）和辛辛那提（UCINN）正在合作建立拟议的中心，UCI是牵头机构。该中心的目标是开发先进的制造技术，用于环境，农业和人类健康的普遍诊断和评估。该中心的目标将通过三个协调的基础和应用研究重点领域来实现：可制造工艺和材料，样品处理和检测以及集成和控制系统。该中心将带来：（a）可转让给工业利益攸关方用于产品开发的先进技术;（B）可供政府实验室用于进一步具体应用开发的技术;（c）教育和培训一批精通低成本可制造微流控生物芯片创新的专业科学家和工程师。 更广泛的影响包括竞争性招聘机制和有吸引力的跨学科合作研究生研究机会，以吸引优秀学生，包括代表性不足的群体的成员。除了传统的技术和会议之外，知识传播还包括一个开源的“微流体功能库”，其中包含按应用和芯片制造工艺组织的微流体回路和可互换组件的设计规格。可扩展的原型设计流程也将传播给学术界和工业界，包括老牌公司和企业家，目标是大幅缩短学习曲线，简化创意到产品的过程。