MRI: Acquisition of an Atmospheric Pressure Ionization Mass Spectrometer for Measurements of Trace Gases and Secondary Organic Aerosol Components in Air

MRI：获取大气压电离质谱仪，用于测量空气中的痕量气体和二次有机气溶胶成分

• 批准号: 1337080
• 负责人: Barbara Finlayson-Pitts
• 金额: $ 27.87万
• 依托单位: University of California-Irvine
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-01 至 2016-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1337080&HistoricalAwards=false
• 关键词: MRI; Acquisition; Atmospheric; Pressure; Ionization

With this award from the Chemistry Major Research Instrumentation Program, Professor Barbara Finlayson-Pitts from University of California Irvine and colleagues Michael Kleinman, Sergey Nizkorodov, Donald Blake and Eric Saltzman will acquire an atmospheric pressure QTrap mass spectrometer that is capable of highly sensitive and specific measurements of both gases and particles. The instrument is capable of carrying out tandem experiments involving molecular analysis of secondary organic aerosols (SOA) using nano-desorption electrospray ionization (nano-DESI), extractive electrospray ionization (EESI), atmospheric solids analysis probe (ASAP) ionization and atmospheric pressure ionization (API). The proposal is aimed at enhancing research and education at all levels, especially in areas such as (a) determination of the products of isoprene photooxidation and the effects of relative humidity on the aerosol composition; (b) real-time measurements of the composition of SOA particles formed in complex volatile organic compounds (VOCs)-nitrogen dioxide-ozone mixtures; (c) elucidation of the efficiency of aerosol mass spectrometry (AMS) for measurements of organic nitrates by comparison to Fourier Transform infrared (FTIR) measurements; (d) measurement of VOCs in tobacco smoke; (e) measurement of nitrogen-containing VOCs from isoprene photooxidation; (f) determination of products of photochemical oxidations of aqueous phase acids and aldehydes; (g) real-time measurement of gaseous precursors and products in an aerosol flow tube during new particle formation and growth; (h) real-time measurement of gaseous p-cymene from the reaction of alpha-pinene with ozone, OH, and nitrate; (i) measurement of oxygen/carbon ratios of SOA and comparison to results from high-resolution electrospray ionization mass spectrometry; (i) real-time measurements of acetone and other oxygenated organic species during a cruise that is part of a North Atlantic gas flux study as well as other research activities.Mass Spectrometry (MS) is one of the key analytical methods used to identify and characterize small quantities of chemical species embedded in complex matrices. In a typical experiment, the components flow into a mass spectrometer where they are ionized into the parent ion and its fragment ions and their masses are measured. This highly sensitive technique allows detection and determination of the structure of molecules in a complex mixture. An instrument with tandem capability provides additional structural identification power through further fragmentation of ions produced in the spectrometer. The instrumentation provided by this award will provide faculty and students in several departments the opportunity to pursue research projects using modern instrumentation not heretofore available at the institution. The research will impact not only the field of Chemistry but also provide important knowledge of atmospheric phenomena. The instrument will also be used in several laboratory courses to train significant numbers of students in the use of this important analytical technique.

通过化学主要研究仪器项目的奖励，来自加州大学欧文分校的Barbara Finlayson-Pitts教授和他的同事Michael Kleinman、Sergey Nizkorodov、Donald Blake和Eric Saltzman将获得一台大气压力QTrap质谱仪，该质谱仪能够对气体和粒子进行高灵敏度和特异性的测量。该仪器能够利用纳米脱附电喷雾电离（nano-DESI）、萃取电喷雾电离（EESI）、大气固体分析探针（ASAP）电离和大气压电离（API）进行二次有机气溶胶（SOA）分子分析的串联实验。该提案旨在加强各级的研究和教育，特别是在以下领域：(a)确定异戊二烯光氧化产物和相对湿度对气溶胶成分的影响；(b)在复杂挥发性有机化合物(VOCs)-二氧化氮-臭氧混合物中形成的SOA颗粒组成的实时测量；(c)通过与傅里叶变换红外（FTIR）测量相比较，阐明了气溶胶质谱（AMS）测量有机硝酸盐的效率；(d)烟草烟雾中挥发性有机化合物的测量；(e)测量异戊二烯光氧化产生的含氮挥发性有机化合物；(f)测定水相酸和醛光化学氧化产物；(g)实时测量新粒子形成和生长过程中气溶胶流管内气体前体和产物；(h)实时测量α -蒎烯与臭氧、OH和硝酸盐反应产生的气态对伞花烃；(i)测定SOA的氧/碳比，并与高分辨率电喷雾电离质谱法的结果进行比较；(i)作为北大西洋气体通量研究以及其他研究活动的一部分，在巡航期间对丙酮和其他含氧有机物种进行实时测量。质谱（MS）是用于鉴定和表征嵌入在复杂基质中的少量化学物质的关键分析方法之一。在一个典型的实验中，这些成分流入质谱仪，在那里它们被电离成母离子和母离子的碎片离子，并测量它们的质量。这种高度灵敏的技术可以检测和确定复杂混合物中的分子结构。具有串联能力的仪器通过在光谱仪中产生的离子进一步破碎提供额外的结构识别能力。该奖项提供的仪器将为多个部门的教师和学生提供机会，使用该机构迄今未提供的现代仪器进行研究项目。这项研究不仅将对化学领域产生影响，而且还将提供有关大气现象的重要知识。该仪器还将用于几个实验课程，以训练大量学生使用这一重要的分析技术。