MRI Consortium: Acquisition of an Integrated System of Instruments for Multichannel Biopotential Recording of In-vitro and In-vivo Experiments

MRI 联盟：采购用于体外和体内实验多通道生物电记录的集成仪器系统

• 批准号: 1337740
• 负责人: Hargsoon Yoon
• 金额: $ 23.96万
• 依托单位: Norfolk State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-01 至 2015-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1337740&HistoricalAwards=false
• 关键词: MRI; Consortium; Acquisition; Integrated; System

An award is made to the Norfolk State University (NSU) to build an integrative research platform for neural recording and analysis and provide the resources for students, faculty and associated collaborators for their research activities from electronic and optical engineering, biology, computer science, nanotechnology, immunology, and neuroscience fields. The addition of this system to the existing research infrastructures will directly benefit and upgrade investigator?s research programs at NSU, Eastern Virginia Medical School and Old Dominion University, as well as the collaborative network capabilities in the Hampton Roads area. Applying the multichannel biopotential recording system, neural and cardiac potentials, and neurochemicals such as neurotransmitters can be measured in-vivo and in-vitro, and analyzed by embedded software. The instrument will be applied for the study of neural mechanisms underlying the interactions under various behavioral, stimuli, and disease conditions. In addition to the biopotential recording, the instrumentation will allow in-vivo assessment of neural sensing devices to be developed by engineering research. Furthermore, in-vivo and in-vitro real-time measurement and monitoring of sensing signal can be applied for the development of novel therapeutic treatment strategies of neurological disorders and degeneration.The outcomes of this synergetic research will be positively transferred to achieve their STEM educational and outreach goals, especially focused for under-represented minority (URM) students in the project?s leading institution, NSU, one of the largest Historically Black Colleges and Universities in the U.S. This project will specifically place a high priority on training of URM students in Hampton Roads region and extend their efforts to URM students nationwide through an aggressive set of research, training and outreach activities utilizing current outreach programs on each campus. The outcomes of this project will be incorporated in their Bioengineering Minor program curriculum. Furthermore, they will also integrate this infrastructure with activity of the newly created Hampton Roads Neuroscience Network.

诺福克州立大学（NSU）获得了一项奖励，用于建立一个神经记录和分析的综合研究平台，并为学生、教师和相关合作者提供资源，用于他们在电子和光学工程、生物学、计算机科学、纳米技术、免疫学和神经科学领域的研究活动。将这一系统添加到现有的研究基础设施中，将直接使研究者受益并提升他们的水平。在NSU，东弗吉尼亚医学院和老道明大学的研究项目，以及汉普顿路地区的协作网络能力。利用多通道生物电位记录系统，可以在体内和体外测量神经和心脏电位以及神经递质等神经化学物质，并通过嵌入式软件进行分析。该仪器将用于研究各种行为、刺激和疾病条件下相互作用的神经机制。除了生物电位记录外，该仪器还将允许通过工程研究开发神经传感装置的体内评估。此外，传感信号的体内和体外实时测量和监测可用于开发神经系统疾病和变性的新型治疗策略。这项协同研究的成果将积极转化为实现STEM教育和推广目标，特别是关注项目中代表性不足的少数民族（URM）学生。该项目将特别优先考虑汉普顿路地区URM学生的培训，并将其努力扩展到全国URM学生，通过一系列积极的研究、培训和推广活动，利用当前每个校园的推广项目。这个项目的成果将被纳入他们的生物工程辅修课程。此外，他们还将把这个基础设施与新创建的汉普顿路神经科学网络的活动结合起来。