MRI: Acquisition of a Multi-Mode Electron Microscope

MRI：购买多模式电子显微镜

• 批准号: 1338346
• 负责人: William Yu
• 金额: $ 19.78万
• 依托单位: Louisiana State University Shreveport
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-01 至 2016-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1338346&HistoricalAwards=false
• 关键词: MRI; Acquisition; Multi; Mode; Electron

With this award from the Chemistry Major Research Instrumentation Program, Professor William Yu from Lousiana State University - Shreveport and colleagues Kui Che, M. Cran Lucas and Thomas Ticich will acquire a high resolution electron microscope (EM) with TEM (transmission), SEM (scanning), STEM and ED (electron difraction) functions. The proposal is aimed at enhancing research and education at all levels, especially in areas such as (a) glycosaminoglycans and podocyte behavior, (b) study of anti-cancer agents based on fusarochromanone (FC101a), (c) magnetic nanocrystals for cancer detection and treatment, (d) inhibiting lymphatogenous tumor metastasis by nanoshell-mediated hyperthermia, (e) TEM analysis of carbon nanostructures synthesized in an ethanol burner, (f) porous stainless steel supported iron oxide nanoparticle membranes for arsenic removal from water, and (g) disruption of crystalline cellulose for efficient enzymatic adsorption and hydrolysis.An electron microscope uses high energy electrons in the characterization of materials. In the transmission mode, a beam of electrons penetrates a thin layer of sample resulting in an image of the sample while in the scanning mode the electrons are used to probe the material. The electron microscope can provide higher resolution and magnification than a microscope using light to probe the material. It can provide useful details of the material down to near atomic size levels. This instrumentation will provide microscopy training and research opportunities to large numbers of students across many fields including chemistry, biology, physics, materials and engineering.

获得化学专业研究仪器计划的这一奖项，来自路易斯安那州立大学-什里夫波特的William Yu教授及其同事Kui Che，M。Cran Lucas和托马斯Ticich将获得一台具有TEM（透射）、SEM（扫描）、STEM和艾德（电子衍射）功能的高分辨率电子显微镜（EM）。该提案旨在加强各级的研究和教育，特别是在以下领域：（a）糖胺聚糖和足细胞行为，（B）基于镰孢色满酮（FC 101 a）的抗癌剂研究，（c）用于癌症检测和治疗的磁性纳米晶体，（d）通过纳米壳介导的高温抑制淋巴源性肿瘤转移，（e）在乙醇燃烧器中合成的碳纳米结构的TEM分析，（f）多孔不锈钢支撑的氧化铁纳米颗粒膜，用于从水中去除砷，和（g）破坏结晶纤维素，用于有效的酶吸附和水解。电子显微镜使用高能电子来表征材料。在透射模式中，电子束穿透样品的薄层，从而产生样品的图像，而在扫描模式中，电子用于探测材料。电子显微镜可以提供比使用光来探测材料的显微镜更高的分辨率和放大率。它可以提供材料的有用细节，低至接近原子大小的水平。该仪器将为化学、生物、物理、材料和工程等多个领域的大量学生提供显微镜培训和研究机会。