Dynamic Materials based on Anchimeric Assistance

本课题由化学系高分子、超分子和纳米化学项目资助。G.斯克里普斯研究所的芬恩将设计和制备基于可逆共价键的动态聚合物。 该方法是开发快速和定量的亲核取代反应的基础上可逆的分子内邻位异构援助，应用这些方法的动态聚合物合成和动态聚合物交联，并适应反应，以建立动态表面。 更广泛的影响包括培训本科生和研究生，通过斯克里普斯研究所和加州大学圣巴巴拉分校的团队之间的合作加强研究和教育的基础设施，并在项目的每一年举办一次当地高中或教师的夏季研究。这项工作将增强我们对动态聚合物的基本理解：长链分子在任何给定时刻具有平均长度，但随着时间的推移不断分裂和改革。 聚合物链是包括塑料在内的许多材料的基本单元，新型聚合物的开发可能会导致生物医学材料，涂料和复合材料的新应用。

In this project funded by the Macromolecular, Supramolecular and Nanochemistry Program of the Chemistry Division, M. G. Finn of The Scripps Research Institute will design and prepare dynamic polymers based upon reversible covalent bonding. The approach is to develop rapid and quantitative nucleophilic substitution reactions based upon reversible intramolecular anchimeric assistance, to apply these methods to dynamic polymer synthesis and dynamic polymer crosslinking, and to adapt the reactions to building dynamic surfaces. The broader impacts involve training undergraduate students and graduate students, enhancing infrastructure for research and education through collaboration between groups at The Scripps Research Institute and UC Santa Barbara, and hosting a local high school or teacher for summer research in each year of the project.This work will enhance our fundamental understanding about dynamic polymers: long chain molecules that have an average length at any given moment but constantly break apart and reform over time. Polymer chains are the fundamental units of many materials, including plastics, and the development of new types of polymers could lead to new applications in biomedical materials, coatings, and composites.