Dynamic Materials based on Anchimeric Assistance

在这个由化学部大分子、超分子和纳米化学项目资助的项目中，斯克里普斯研究所的M. G. Finn将设计和制备基于可逆共价键的动态聚合物。该方法是基于可逆的分子内嵌合辅助发展快速、定量的亲核取代反应，将这些方法应用于动态聚合物合成和动态聚合物交联，并使反应适应于构建动态表面。更广泛的影响包括培训本科生和研究生，通过斯克里普斯研究所和加州大学圣巴巴拉分校的小组之间的合作，加强研究和教育的基础设施，并在每年的项目中接待一名当地高中或教师进行暑期研究。这项工作将增强我们对动态聚合物的基本理解：长链分子在任何给定时刻都具有平均长度，但随着时间的推移不断分解和重组。聚合物链是包括塑料在内的许多材料的基本单元，新型聚合物的开发可能会在生物医学材料、涂料和复合材料方面带来新的应用。

In this project funded by the Macromolecular, Supramolecular and Nanochemistry Program of the Chemistry Division, M. G. Finn of The Scripps Research Institute will design and prepare dynamic polymers based upon reversible covalent bonding. The approach is to develop rapid and quantitative nucleophilic substitution reactions based upon reversible intramolecular anchimeric assistance, to apply these methods to dynamic polymer synthesis and dynamic polymer crosslinking, and to adapt the reactions to building dynamic surfaces. The broader impacts involve training undergraduate students and graduate students, enhancing infrastructure for research and education through collaboration between groups at The Scripps Research Institute and UC Santa Barbara, and hosting a local high school or teacher for summer research in each year of the project.This work will enhance our fundamental understanding about dynamic polymers: long chain molecules that have an average length at any given moment but constantly break apart and reform over time. Polymer chains are the fundamental units of many materials, including plastics, and the development of new types of polymers could lead to new applications in biomedical materials, coatings, and composites.