STTR Phase I: Diode pumped Modelocked Titanium Sapphire Fiber Laser

这个小企业技术转让（STTR）第一阶段项目将发展世界？基于可见光激光二极管泵浦钛蓝宝石光纤的第一个商业二极管泵浦锁模钛蓝宝石光纤激光器。通过使用直接半导体激光二极管泵浦作为引擎，并且光纤作为增益介质，这种两级光纤激光器设计方法代表了远离传统的脆弱、昂贵的笨重的四级固态晶体激光器腔的范例转移，四级固态晶体激光器腔利用二极管泵浦的二次谐波绿色激光器来泵浦钛蓝宝石。 因此，该项目具有实质性的技术价值，因为它旨在开创和商业化一类新的可见激光二极管泵浦光纤激光器技术，并提供大量的学习激光和光纤材料技术。该项目对生物医学成像界的更广泛的影响/商业潜力将是变革性的，将先进的非线性成像技术的采用扩展到精英研究机构之外，并将其提供给医院和进行生物研究的商业公司中更广泛的生物医学成像社区。 该激光器能够实现多光子吸收和单光子发射过程，用于深度，高分辨率的活组织成像，为研究干细胞生物学，人类疾病的细胞效应，生理学，神经生物学，胚胎学和组织工程提供见解。 此外，激光？的高峰功率具有烧蚀性，可用于眼科和烧蚀手术、精密材料处理和纹身去除。 该系统旨在满足大型且不断增长的多光子成像和生物医学系统市场的需求，并取代过于昂贵和复杂的锁模钛蓝宝石激光器系统。

This Small Business Technology Transfer (STTR) Phase I project will develop world?s first commercial diode pumped mode-locked titanium sapphire fiber laser based on visible laser diodes pumping a titanium sapphire fiber. By using direct semiconductor laser diode pumps as the engine, and fiber as the gain medium, this two stage fiber laser design approach represents a paradigm shift away from conventional fragile, expensive bulky four stage solid state crystal laser cavities, which utilize diode pumped second harmonic green lasers for pumping titanium sapphire. Therefore, this project has substantial technical merit because it aims to pioneer and commercialize a new class of visible laser diode pumped fiber laser technology and provide substantial learning into laser and fiber optic materials technology.The broader impact/commercial potential of this project for the biomedical imaging community would be transformative, expanding the adoption of advanced nonlinear imaging techniques beyond the elite research institutions, and making them available to the broader biomedical imaging community in hospitals and commercial companies conducting bio-research. The laser enables a multi-photon absorption and single photon emission process for deep, high resolution live tissue imaging that provides insights into study stem cell biology, the cellular effects of human disease, physiology, neurobiology, embryology and tissue engineering. Additionally, the laser?s high peak powers has ablative that can be leveraged to address ophthalmic and ablative surgery, precision materials processing, and tattoo removal. This system is designed to address the needs of the large and growing multi-photon imaging and biomedical systems market segment, and replace the excessively expensive and complex modelocked titanium sapphire lasers systems.