STTR Phase I: Diode pumped Modelocked Titanium Sapphire Fiber Laser

这个小型企业技术转移（STTR）第一期项目将发展世界？第一个商用二极管泵浦锁模钛蓝宝石光纤激光器基于可见激光二极管泵浦钛蓝宝石光纤。采用直接半导体激光二极管泵浦作为发动机，光纤作为增益介质，这种两级光纤激光器的设计方法代表了一种范式的转变，从传统的脆弱，昂贵的笨重的四级固体晶体激光腔，利用二极管泵浦的二次谐波绿色激光器抽运钛蓝宝石。因此，该项目具有很大的技术价值，因为它旨在开拓和商业化一种新型的可见激光二极管泵浦光纤激光技术，并为激光和光纤材料技术提供大量的学习。该项目对生物医学成像社区的广泛影响/商业潜力将是变革性的，将先进非线性成像技术的采用扩大到精英研究机构之外，并使其可用于医院和商业公司进行生物研究的更广泛的生物医学成像社区。该激光器可实现多光子吸收和单光子发射过程，用于深度、高分辨率活组织成像，为研究干细胞生物学、人类疾病的细胞效应、生理学、神经生物学、胚胎学和组织工程提供见解。此外，激光？S的峰值功率具有消融，可用于解决眼科和消融手术，精密材料加工和纹身去除。该系统旨在满足庞大且不断增长的多光子成像和生物医学系统细分市场的需求，并取代过于昂贵和复杂的模型锁定钛蓝宝石激光器系统。

This Small Business Technology Transfer (STTR) Phase I project will develop world?s first commercial diode pumped mode-locked titanium sapphire fiber laser based on visible laser diodes pumping a titanium sapphire fiber. By using direct semiconductor laser diode pumps as the engine, and fiber as the gain medium, this two stage fiber laser design approach represents a paradigm shift away from conventional fragile, expensive bulky four stage solid state crystal laser cavities, which utilize diode pumped second harmonic green lasers for pumping titanium sapphire. Therefore, this project has substantial technical merit because it aims to pioneer and commercialize a new class of visible laser diode pumped fiber laser technology and provide substantial learning into laser and fiber optic materials technology.The broader impact/commercial potential of this project for the biomedical imaging community would be transformative, expanding the adoption of advanced nonlinear imaging techniques beyond the elite research institutions, and making them available to the broader biomedical imaging community in hospitals and commercial companies conducting bio-research. The laser enables a multi-photon absorption and single photon emission process for deep, high resolution live tissue imaging that provides insights into study stem cell biology, the cellular effects of human disease, physiology, neurobiology, embryology and tissue engineering. Additionally, the laser?s high peak powers has ablative that can be leveraged to address ophthalmic and ablative surgery, precision materials processing, and tattoo removal. This system is designed to address the needs of the large and growing multi-photon imaging and biomedical systems market segment, and replace the excessively expensive and complex modelocked titanium sapphire lasers systems.