CAREER: Microstructure-Specific Machining Strategies for Bone

这项教师早期职业发展（Career）计划的总体研究目标是研究骨微结构成分对其加工反应的基本影响。特别是，该研究将验证这样一个假设，即骨骼微结构成分中与年龄/骨骼类型相关的变化会影响其关键的加工响应，如表面完整性、切削力、刀具磨损和切屑形态。实验研究的目的是将骨微观结构相的特性与其加工反应联系起来。基于微观结构的有限元建模研究将旨在识别加工过程中遇到的年龄/骨类型特定的失效机制。该职业奖的教育目标是在纽约州北部地区招募、教育和发展下一代制造业专业人士。教育重点领域包括：1)开发一个基于乐高的动手模块，让6 -12年级的学生接触到微制造技术；2)开发先进的制造业课程，促进高中女生的制造业教育和职业；3)加强伦斯勒理工学院的制造业教育。该研究结果将对涉及任何形式的骨加工的外科手术程序产生影响。特别是，对于全关节置换手术，研究结果可能会减少患者的恢复时间和翻修手术的可能性，这两项手术目前对美国的医疗保健系统造成了沉重的经济负担。这项研究还将导致数十亿美元的骨手术器械和外科医生培训平台市场的产品创新。教育活动旨在解决当前国家在先进制造业领域面临的人力资源危机。为6 -12年级学生，特别是高中女生开发的教育模块和课程，有可能将K-12年级的学生输送到与制造业相关的教育领域和职业。

The overarching research objective of this Faculty Early Career Development (CAREER) Program award is to investigate the fundamental effect of bone microstructural components on its machining responses. In particular, the research will test the hypothesis that age/bone-type related variations seen in the microstructural components of bone have an influence on its critical machining responses such as surface integrity, cutting forces, tool-wear and chip morphology. The experimental studies will be aimed at linking the properties of bone microstructural phases to its machining responses. The microstructure-based finite element modeling study will be aimed at identifying age/bone-type-specific failure mechanisms encountered during machining. The educational objective of this CAREER award is to recruit, educate and develop the next generation of manufacturing professionals in the upstate New York region. The educational thrust areas include: 1) Developing a Lego-based, hands-on module to expose 6th-12th graders to micro-manufacturing technologies; 2) Developing an advanced manufacturing curriculum that promotes manufacturing education and careers to high-school girls; and 3) Enhancing the manufacturing education efforts at Rensselaer Polytechnic Institute.The research findings will have implications for surgical procedures involving any form of bone machining. In particular, for total joint replacement surgeries the findings are likely to reduce patient recovery times and the probability of revision surgeries, both of which currently place a heavy economic burden on the healthcare system in the United States. This research will also result in product innovations in the multi-billion dollar market pertaining to bone surgery instrumentation and surgeon training platforms. The educational activities are geared towards addressing the current human resource crisis facing the nation in the area of advanced manufacturing. The educational module and curriculum being developed for the 6th-12th grade students, especially high school girls, has the potential to funnel K-12 students to manufacturing-related educational fields and careers.