The 2020 Vision: Building Research, Education, and Innovation Partnerships for South Dakota

南达科他州生物化学时空网络资源(BioSNTR)项目将开发通过生物科学和信息学的科学进步来提高农业生产力的方法。BioSNTR将使用成像和分子生物学来绘制植物和动物细胞的生化结构图。通过应用有关分子电路向植物细胞发出生长和功能信号的方式的新知识，将开发提高作物产量的技术。BioSNTR活动的结果可能会对南达科他州的农业产生积极的经济影响。该项目涉及南达科他州的所有学院和大学，并正在扩大妇女、美洲原住民和残疾人在科学、技术、工程和数学方面的参与。BioSNTR将培养一支在生物科学和信息学方面具有专业知识的熟练、多样化的技术队伍。南达科他州的学生将通过实习机会获得创业和工业经验。BioSNTR正在南达科他州立大学实施一项新的生物化学博士项目，并在南达科他州的几所大学加强计算科学项目。技术描述南达科他州刺激竞争研究的实验计划(EPSCoR)正在创建生化时空网络资源(BioSNTR)，这是一个跨学科的、多机构的系统生物科学研究和教育计划。BioSNTR推动了成像和分子生物学的发展，以研究参与细胞信号传递的复杂分子电路。了解这一过程对于合理操纵植物和动物系统中的细胞-生物材料界面至关重要。BioSNTR的愿景是以足够的分辨率绘制这种分子电路的生化结构图，以便能够对细胞功能的有效控制和操作做出定量预测。BioSNTR的技术进步将导致作物产量、动物福利和人类健康的改善。通过BioSNTR，南达科他州EPSCoR正在改善该州-S在生物科学和信息学领域的物质基础设施和人力资源，这是南达科他州和全国的两个科学增长领域。

Non-technical DescriptionThe South Dakota Biochemical Spatiotemporal NeTwork Resource (BioSNTR) project will develop ways to increase agricultural productivity through scientific advances in bioscience and informatics. The BioSNTR will use imaging and molecular biology to map the biochemical architecture of plant and animal cells. Technologies to improve crop yields will be developed by applying new knowledge about the ways that molecular circuits signal plant cells to grow and function. Results from BioSNTR activities are likely to have positive economic outcomes for South Dakota's agriculture.The project involves all of the colleges and universities in South Dakota, and is broadening the participation of women, Native Americans and persons with disabilities in science, technology, engineering, and mathematics. The BioSNTR will develop a skilled, diverse technical workforce with expertise in bioscience and informatics. South Dakota students will gain entrepreneurial and industrial experience through internship opportunities. BioSNTR is implementing a new PhD program in biochemistry at South Dakota State University and strengthening the computational science programs in several South Dakota universities.Technical DescriptionThe South Dakota Experimental Program to Stimulate Competitive Research (EPSCoR) is creating the Biochemical Spatiotemporal NeTwork Resource (BioSNTR), a transdisciplinary, multi-institutional program for systems bioscience research and education. BioSNTR advances imaging and molecular biology to investigate the sophisticated molecular circuit involved in cell signaling. Understanding this process is essential for rational manipulation of the cell-biomaterial interface in plant and animal systems. The vision of BioSNTR is to map the biochemical architecture of this molecular circuit with sufficient resolution that quantitative predictions can be made for effective control and manipulation of cell function. Technological advances from BioSNTR will lead to improvements in crop yields, animal welfare, and human health. Through BioSNTR, South Dakota EPSCoR is improving the state?s physical infrastructure and human workforce in the areas of bioscience and informatics, two scientific growth fields for South Dakota and the nation.