Physics of Cancer Imaging Workshop Held at the Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital. Dates for the meeting are Nov 5-6, 2013

癌症成像物理研讨会在马萨诸塞州总医院 Athinoula A. Martinos 生物医学成像中心举行。

• 批准号: 1400499
• 负责人: Herbert Levine
• 金额: $ 4.96万
• 依托单位: William Marsh Rice University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-12-01 至 2017-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1400499&HistoricalAwards=false
• 关键词: Physics; Cancer; Imaging; Workshop; Held

Imaging plays a critical role in the diagnosis, staging, and in the assessment of therapeutic response in cancer. Imaging is of course a broad discipline encompassing a variety of rather different modalities (X-ray, MRI, PET) and analysis techniques. Principles from the fields of physics and mathematics can be applied to the analysis and interpretation of current imaging techniques as well to development of novel imaging techniques. A key issue for the field is the extent to which different methods can be used synergistically to gain additional information. Another key issue is improving the usefulness of specialized contrast agents to get around existing limitations in signal to noise and/or spatial resolution. To address the aforementioned challenges, the organizers will convene a two-day focused workshop to be held in the Boston area. The two-day highly focused meeting will have a full agenda of topics at the intersection of physics and mathematics and cancer imaging. The meeting will be oriented around a high level of interactions between participants, focusing on problems where fundamental physical and mathematical principles and advanced imaging can be leveraged to make progress towards cancer diagnosis and treatment. Most of each session will be devoted to active discussion within a small group of invitees, who span both the physics and engineering of advanced imaging and biologists and clinicians at the forefront of cancer biology and treatment. This will be the first informal workshop that tries to create an integrated picture of what can be accomplished via noninvasive methods in human patients. It is expected that the white paper generated as part of the meeting follow-up will have a very large impact on the direction of scientific research in this essential area. Bringing together experts from different parts of this field can be expected to lead to new directions and ultimately better imaging "products" for the practicing oncologist. At a more basic science level, it is expected that the ideas generated may be useful for other applications of imaging in biology and biomedicine. To facilitate the spread of ideas generated by this meeting to the rest of the community, synopses of various talks as well as an overall summary will be posted at http://www.martinos.org/martinos/poahi/ and linked to the community Physics of Cancer website: http://physicsandcancer.org/

成像在癌症的诊断、分期和治疗反应评估中起着至关重要的作用。成像当然是一门广泛的学科，涵盖各种不同的模式（X 射线、MRI、PET）和分析技术。物理和数学领域的原理可应用于当前成像技术的分析和解释以及新型成像技术的开发。该领域的一个关键问题是不同方法可以在多大程度上协同使用以获得额外信息。另一个关键问题是提高专用造影剂的实用性，以克服现有的信噪比和/或空间分辨率限制。为了应对上述挑战，主办方将在波士顿地区举办为期两天的重点研讨会。为期两天的高度集中的会议将在物理、数学和癌症成像的交叉领域制定完整的议程。会议将以参与者之间的高水平互动为导向，重点讨论可以利用基本物理和数学原理以及先进成像技术在癌症诊断和治疗方面取得进展的问题。每场会议的大部分时间将致力于一小群受邀者的积极讨论，这些受邀者涵盖先进成像的物理和工程领域以及处于癌症生物学和治疗前沿的生物学家和临床医生。这将是第一个非正式研讨会，试图全面了解通过非侵入性方法对人类患者可以实现的目标。预计作为会议后续部分产生的白皮书将对这一重要领域的科学研究方向产生非常大的影响。来自该领域不同领域的专家聚集在一起有望为执业肿瘤学家带来新的方向并最终带来更好的成像“产品”。在更基础的科学层面上，预计所产生的想法可能对生物学和生物医学中成像的其他应用有用。为了促进本次会议产生的想法向社区其他成员传播，各种演讲的概要以及总体摘要将发布在 http://www.martinos.org/martinos/poahi/ 上，并链接到社区癌症物理学网站：http://physicalsandcancer.org/