NSF NPGI Postdoctoral Fellowship in Biology FY 2014

这一行动为NSF国家植物基因组计划2014财年生物学博士后研究奖学金提供了资金。该奖学金支持在东道主实验室为该研究员制定的研究和培训计划，该研究员还提出了扩大生物学参与度的计划。马修·津克格拉夫的这项研究和培训计划的标题是“杨树维管形成层发育的转录调控和基因网络”。该奖学金的主办机构是美国林业局和加州大学戴维斯分校，赞助科学家是安德鲁·格罗弗博士和弗拉基米尔·菲尔科夫博士。这项研究将带来对树木次生木质生长的更基本的理解。次生生长是碳循环的重要组成部分，尤其是碳固存，也是森林生态的一个重要方面。该项目的培训目标包括为研究员提供学习先进分子遗传技术和计算生物学的机会，并发展独立的职业生涯。更广泛的影响包括指导本科生，专业发展，以及对加州和威斯康星州社区的公众宣传。拟议的研究重点是二次生长，木本树的径向生长来自维管形成层分生组织。次生生长提供了了解树木生长的基本方面的机会，这些方面具有直接的经济和环境重要性。这个项目将使用基因组工具来表征转录因子，这些转录因子在模式林木杨树的二次生长期间调节基因表达。这将允许使用先进的计算方法来研究二次生长过程中转录调控的基本特征，包括转录因子的组合结合在调控基因表达中的作用，以及转录网络的拓扑结构。这项研究的结果将使人们更全面地了解树木二次生长所涉及的基因和基因网络，这些基因和基因网络对碳循环和生态学非常重要。

This action funds an NSF National Plant Genome Initiative Postdoctoral Research Fellowship in Biology for FY 2014. The fellowship supports a research and training plan in a host laboratory for the Fellow who also presents a plan to broaden participation in biology. The title of the research and training plan for this fellowship to Matthew Zinkgraf is "Transcriptional Regulation and Gene Networks Underlying Vascular Cambium Development in Populus". The host institutions for the fellowship are the US Forest Service and the University of California, Davis and the sponsoring scientists are Drs. Andrew Groover and Vladimir Filkov.The research will lead to a more fundamental understanding of secondary, woody growth in trees. Secondary growth is an important part of the carbon cycle, specifically carbon sequestration, and an integral aspect of forest ecology. The training objectives of this project include learning opportunities in advanced molecular genetic techniques and computational biology for the Fellow and the development of an independent career. Broader impacts include mentoring undergraduate students, professional development, and public outreach to communities in California and Wisconsin.The proposed research focuses on secondary growth, the radial growth of woody tree stems from the vascular cambium meristem. Secondary growth presents opportunities to understand fundamental aspects of tree growth that are of direct economic and environmental importance. This project will use genomic tools to characterize transcription factors that regulate gene expression during secondary growth in the model forest tree, Populus. This will allow for the use advanced computational methods to examine fundamental features of transcriptional regulation during secondary growth, including the role of combinatorial binding of transcription factors in regulating gene expression, and the topology of transcriptional networks. The outcomes of the research will lead to a fuller understanding of the genes and gene networks involved in secondary growth in trees, important to carbon cycling and ecology.