Cell Phone Based Polarized Light Imaging

基于手机的偏振光成像

• 批准号: 1402846
• 负责人: Gerard Cote
• 金额: $ 48.18万
• 依托单位: Texas A&M Engineering Experiment Station
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-06-01 至 2018-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1402846&HistoricalAwards=false
• 关键词: Cell; Phone; Based; Polarized; Light

1402846CoteThe goal of this proposal is to develop a transformative low cost, high quality, noninvasive, cellphone-based, optical polarimetric imaging system for point-of-care applications. The specific aims are to design, model, build, and test the system and to develop android based applications for controlling cell phone camera features and perform image processing. This system will utilize a single lens on-chip white light polarized imaging to aid in the diagnosis of several diseases through the detection of variations in the linear states of polarized light as it passes through tissue or blood sample. There are many conditions that induce changes in polarized light and the device is meant to assist medical professionals in the clinic and in low resource settings in the proper diagnosis of these conditions. The initial applications for developing this device include in vivo diagnosis of skin cancers such as basal cell carcinoma (BCC), melanoma, and squamous cell carcinoma (SCC) and in vitro detection of malaria in the lab or in the field.

1402846 Cote该提案的目标是开发一种变革性的低成本、高质量、非侵入性、基于手机的光学偏振成像系统，用于即时护理应用。具体目标是设计，建模，构建和测试系统，并开发基于Android的应用程序，用于控制手机摄像头功能和执行图像处理。该系统将利用单个透镜片上白色光偏振成像，以通过检测偏振光穿过组织或血液样品时偏振光的线性状态的变化来帮助诊断几种疾病。有许多条件会引起偏振光的变化，该设备旨在帮助临床和低资源环境中的医疗专业人员正确诊断这些条件。开发该设备的最初应用包括皮肤癌的体内诊断，如基底细胞癌（BCC），黑色素瘤和鳞状细胞癌（SCC），以及实验室或现场疟疾的体外检测。