Workshop: Advanced Biomanufacturing, July 17-20, 2014, Talloires, France

PI: Kaplan, David L.提案编号：1439418机构：Tufts University标题：研讨会：先进生物制造，2014年7月17日至20日，法国塔卢瓦尔。为期两天半的先进生物制造研讨会计划于2014年7月17日至20日在法国塔卢瓦尔举行。研讨会的目标是建立在之前nsf赞助的研讨会（2013年7月25日至26日在弗吉尼亚州阿灵顿举行）的成果之上。这一先前的活动包括学术界、工业界和政府的参与，并在一份已出版的讲习班报告中报告了结果。本报告的一项关键内容是与会者提出的一套建议，其中出现了两项需要。一个需要是扩大该领域的科学障碍，进行更集中的讨论，为未来的方向提供明确的指导，以帮助该领域向前发展。第二个需要是召集一个小组，与来自欧洲同事的更广泛代表进行更有针对性的讨论，因为最初的研讨会只包括美国同事。这样的讨论将有助于确定国际合作机会，并细化具体需求和想法的路线图，以解决先进生物制造领域的障碍。结果将包括确定需要克服的挑战和实现对科学、规模、就业和经济增长的最大影响的机会，并将生成一份讲习班报告。研讨会将由David Kaplan （Tufts University, david.kaplan@tufts.edu）和Jason Kelly， Ginkgobioworks, Inc. （jason@ginkgobioworks.com）主持。研讨会的主题是基于生物制造在美国和世界各地的快速增长和潜在影响，包括合成生物学，生物聚合物工程，3D打印，组织工程和许多相关主题。这一领域的进步有可能将制造业的工作岗位带回美国，并引领一场科技革命，在这场革命中，阳光、有机体、综合合成和加工以及新颖的生物方法和独创性将为当前的石化衍生原料和工艺提供替代方案，并将指导下一代生物医学治疗方法的发展，特别是那些基于活细胞输送的生物医学治疗方法。在过去的10-15年里，随着基因组学和蛋白质组学、细胞生物学、工艺工程和设计以及系统集成的进步，支持先进生物制造的科学工具不断涌现。会议计划将提供先进生物制造的全面概述，包括分子方法和构建模块，细胞方法，组装和聚合物，组织和器官方法以及系统集成。它还将提供对未来挑战和机遇的洞察，并将促进这一新兴研究领域的国际合作。

PI: Kaplan, David L. Proposal Number: 1439418Institution: Tufts University Title: Workshop: Advanced Biomanufacturing, July 17-20, 2014, Talloires, FranceA two and half day workshop on Advanced Biomanufacturing is planned for July 17-20, 2014 in Talloires, France. The goal of the workshop is to build upon the outcomes generated from the prior NSF-sponsored workshop (held July 25-26, 2013 in Arlington, Virginia). This prior event included participation from academia, industry and government and the outcomes were reported in a published workshop report. A key element of this report was a set of recommendations from the participants, out of which two needs emerged. One need is to amplify on the scientific barriers in the field with more focused discussions to provide clear guidance on future directions to help the field move forward. The second need is to bring a small group together to hold more focused discussions with broader representation from European colleagues, as the initial workshop only included US colleagues. Such discussions will help identify international collaboration opportunities as well as refine roadmaps of specific needs and ideas to address the barriers in the field of Advanced Biomanufacturing. The outcomes will include the identification of challenges to overcome and opportunities to achieve maximal impact on science, scale up, jobs and economic growth and a workshop report will be generated. The workshop will be run by David Kaplan (Tufts University, david.kaplan@tufts.edu) and Jason Kelly, Ginkgobioworks, Inc. (jason@ginkgobioworks.com)The workshop topic is significant and timely based on the rapid growth and potential impact of biomanufacturing in the US and around the world, including synthetic biology, biopolymer engineering, 3D printing, tissue engineering and many related topics. Advances in this field have the potential to return manufacturing jobs to the US and lead a scientific and technological revolution wherein sunlight, organisms, integrated synthesis and processing and novel biological approaches and ingenuity would provide alternatives to current petrochemically-derived feedstocks and processes and will also guide the development of the next generation of biomedical therapeutics, especially those based on the delivery of living cells. The scientific tools to support advanced biomanufacturing have been emerging over the past 10-15 years, empowered by advances in genomics and proteomics, cell biology, process engineering and design and systems integration. The conference program will provide a comprehensive overview of Advanced Biomanufacturing, including molecular approaches and building blocks, cellular approaches, assemblies and polymers, tissue and organ approaches, and systems integration. It will also provide insight into future challenges and opportunities and will catalyze international collaborations in this emerging area of research.