Workshop: Advanced Biomanufacturing, July 17-20, 2014, Talloires, France

研讨会：先进生物制造，2014 年 7 月 17-20 日，法国塔卢瓦尔

• 批准号: 1439418
• 负责人: David Kaplan
• 金额: $ 2万
• 依托单位: Tufts University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1439418&HistoricalAwards=false
• 关键词: Workshop; Advanced; Biomanufacturing; July; 17

PI: Kaplan, David L. Proposal Number: 1439418Institution: Tufts University Title: Workshop: Advanced Biomanufacturing, July 17-20, 2014, Talloires, FranceA two and half day workshop on Advanced Biomanufacturing is planned for July 17-20, 2014 in Talloires, France. The goal of the workshop is to build upon the outcomes generated from the prior NSF-sponsored workshop (held July 25-26, 2013 in Arlington, Virginia). This prior event included participation from academia, industry and government and the outcomes were reported in a published workshop report. A key element of this report was a set of recommendations from the participants, out of which two needs emerged. One need is to amplify on the scientific barriers in the field with more focused discussions to provide clear guidance on future directions to help the field move forward. The second need is to bring a small group together to hold more focused discussions with broader representation from European colleagues, as the initial workshop only included US colleagues. Such discussions will help identify international collaboration opportunities as well as refine roadmaps of specific needs and ideas to address the barriers in the field of Advanced Biomanufacturing. The outcomes will include the identification of challenges to overcome and opportunities to achieve maximal impact on science, scale up, jobs and economic growth and a workshop report will be generated. The workshop will be run by David Kaplan (Tufts University, [e-mail]) and Jason Kelly, Ginkgobioworks, Inc. ([e-mail])The workshop topic is significant and timely based on the rapid growth and potential impact of biomanufacturing in the US and around the world, including synthetic biology, biopolymer engineering, 3D printing, tissue engineering and many related topics. Advances in this field have the potential to return manufacturing jobs to the US and lead a scientific and technological revolution wherein sunlight, organisms, integrated synthesis and processing and novel biological approaches and ingenuity would provide alternatives to current petrochemically-derived feedstocks and processes and will also guide the development of the next generation of biomedical therapeutics, especially those based on the delivery of living cells. The scientific tools to support advanced biomanufacturing have been emerging over the past 10-15 years, empowered by advances in genomics and proteomics, cell biology, process engineering and design and systems integration. The conference program will provide a comprehensive overview of Advanced Biomanufacturing, including molecular approaches and building blocks, cellular approaches, assemblies and polymers, tissue and organ approaches, and systems integration. It will also provide insight into future challenges and opportunities and will catalyze international collaborations in this emerging area of research.

PI：Kaplan，大卫L. 提案编号：1439418机构：塔夫茨大学标题：研讨会：先进的生物制造，2014年7月17日至20日，塔卢瓦尔，法国一个为期两天半的先进生物制造研讨会计划于2014年7月17日至20日在塔卢瓦尔，法国。 研讨会的目标是建立在先前NSF主办的研讨会（2013年7月25日至26日在弗吉尼亚州阿灵顿举行）产生的成果的基础上。 学术界、工业界和政府参加了这一先前的活动，并在一份出版的研讨会报告中报告了成果。 该报告的一个关键要素是与会者提出的一套建议，其中提出了两项需要。一个需要是通过更有针对性的讨论来扩大该领域的科学障碍，为未来的方向提供明确的指导，以帮助该领域向前发展。第二个需要是召集一个小组，与来自欧洲同事的更广泛代表进行更有针对性的讨论，因为最初的研讨会只包括美国同事。这些讨论将有助于确定国际合作机会，并完善具体需求和想法的路线图，以解决先进生物制造领域的障碍。 成果将包括确定需要克服的挑战和对科学、扩大规模、就业和经济增长产生最大影响的机会，并将编写一份研讨会报告。 研讨会将由大卫卡普兰（塔夫茨大学，david. tufts.edu）和杰森凯利，Ginkgobioworks公司。（[e-mail]）基于美国和世界各地生物制造的快速增长和潜在影响，研讨会的主题是重要和及时的，包括合成生物学，生物聚合物工程，3D打印，组织工程和许多相关主题。 这一领域的进展有可能使制造业工作岗位回到美国，并引领一场科学和技术革命，其中阳光、生物体、综合合成和加工以及新颖的生物方法和独创性将为目前的石化衍生原料和工艺提供替代品，并将指导下一代生物医学疗法的开发，特别是基于活细胞递送的生物医学疗法。支持先进生物制造的科学工具在过去10-15年中不断出现，并受到基因组学和蛋白质组学、细胞生物学、工艺工程和设计以及系统集成方面的进步的推动。 会议计划将提供先进生物制造的全面概述，包括分子方法和构建模块，细胞方法，组装和聚合物，组织和器官方法以及系统集成。 它还将提供对未来挑战和机遇的洞察力，并将促进这一新兴研究领域的国际合作。