Student Travel Support for Harmony 2015

数据交换标准对任何领域的发展都至关重要。它们使研究人员和从业人员能够可靠地交换信息，应用各种工具解决问题，并重现科学结果。生物学计算建模网络（COMBINE）创建于2010年，旨在组织系统生物学的标准化工作。这项工作包括用于数学建模的系统生物学标记语言（SBML）；生物通路交换语言（BioPAX）用于描述通路；以及用于视觉表示的系统生物学图形符号（SBGN）。另一方面，合成生物学社区正在开发合成生物学开放语言（SBOL）。虽然合成生物学有许多独特的要求，但也有许多重叠的特征，例如需要构建数学模型、描述途径和提供视觉表示。加入这些努力是很重要的，这样，合成生物学社区就可以利用现有的标准来实现工具和其他基础设施的共享。该项目将有助于这两个社区在4月20日至24日在德国维滕贝格举行的COMBINE的HARMONY 2015会议上会面（http://co.mbine.org/events/HARMONY_2015）。像这样的研讨会有助于在这些标准的开发中取得进展。目前，大多数标准化工作要么没有资金支持，要么只有非常有限的支持。实际上，这些标准的成功是由于许多人贡献时间参与讨论、编写规范、担任标准编辑和参加研讨会。许多从事SBOL发展的个人都是美国的学生，否则他们很难找到参加这次会议的资金。因此，该项目将帮助支持这些从事SBOL标准工作的美国学生前往德国参加HARMONY 2015的差旅费。这不仅对这些学生来说是一次宝贵的经历，而且还将极大地增强我们的目标，即将合成生物学的研究人员与系统生物学的研究人员聚集在一起，从而实现集成标准和共享软件和基础设施。本次研讨会的目标将是：(1)发展系统和合成生物学研究人员之间的协同关系；(2)为系统和合成生物学的标准开发提供更紧密的整合；(3)与建模人员和实验人员进行联系；(4)讨论如何协调努力，倡导在出版物和档案数据库中使用标准，以提高科学结果的可重复性。

Standards for data exchange are critical to the development of any field. They enable researchers and practitioners to exchange information reliably, apply a variety of tools to their problems, and reproduce scientific results. The COmputational MOdeling in Biology NEtwork (COMBINE) was created in 2010 to organize standardization efforts for systems biology. This effort includes, among others, the systems biology markup language (SBML) for mathematical modeling; the biological pathways exchange language (BioPAX) for describing pathways; and the systems biology graphical notation (SBGN) for visual representations. In a separate effort, the synthetic biology community is developing the synthetic biology open language (SBOL). While synthetic biology has many unique requirements, there are also a lot of overlapping features such as the need to construct mathematical models, describe pathways, and provide visual representations. It is important to join these efforts, such that, the synthetic biology community can leverage existing standards enabling the sharing of tools and other infrastructure. This project will help enable these two communities to meet together at COMBINE's HARMONY 2015 meeting to be held in Wittenberg, Germany on April 20th to 24th (http://co.mbine.org/events/HARMONY_2015). Workshops like this one are instrumental in making progress in the development of these standards. Currently, most standardization efforts are either unfunded or only have very limited support. Indeed, the success of these standards has been due to the donation of time from many individuals to participate in discussions, write specifications, serve as standard editors, and attend workshops. Many of these individuals working on the development of SBOL are students based in the US who would otherwise find it difficult to find the funds to attend this meeting. Therefore, this project would help support travel expenses for these US-based students working on the SBOL standard to travel to Germany for HARMONY 2015. Not only would this be a valuable experience for these students, but it would also greatly enhance our goal of bringing together researchers in synthetic biology with those working in systems biology leading to integrated standards and shared software and infrastructure. The goals of this workshop will be to (1) develop synergistic relationships between systems and synthetic biology researchers; (2) provide a tighter integration of standard development for systems and synthetic biology; (3) perform outreach to modelers and experimentalists; and (4) discuss a coordinated effort to advocate the use of standards in publications and archival databases to enhance reproducibility of scientific results.