I-Corps: Volatile Organic Compound Sensors using Conducting Polymer and Nanocomposite Blends deposited by Resonant Infrared, Matrix-Assisted Pulsed Laser Evaporation

I-Corps:使用通过共振红外、基质辅助脉冲激光蒸发沉积的导电聚合物和纳米复合材料混合物制成的挥发性有机化合物传感器

基本信息

  • 批准号:
    1450511
  • 负责人:
  • 金额:
    $ 5万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2014
  • 资助国家:
    美国
  • 起止时间:
    2014-08-01 至 2015-07-31
  • 项目状态:
    已结题

项目摘要

There is a large number of diabetics for whom a simple breath test to determine glucose abnormalities would be deemed superior to the current standard blood test. Development of a non-invasive method to monitor blood glucose that mirrors the accuracy of the painful blood test would revolutionize not only the lives of diabetics, but also the lives of the physicians who monitor their health. The painful blood test that is currently the standard monitoring method is potentially expensive, and it also deters regular monitoring of glucose - often with dangerous outcomes. It is especially dangerous for diabetics who have hypoglycemia unawareness, in which case, only the glucose test will alert the person to the dangerously low blood sugar levels that can lead to coma or even death.This work will develop gas sensors for detection of volatile organic compounds (VOCs) in exhaled human breath that act as biomarkers of internal bodily processes, specifically those processes existing uniquely in diabetes patients. The gas sensors comprise organic thin-films deposited by resonant infrared, matrix-assisted pulsed laser evaporation (RIR-MAPLE). RIR-MAPLE provides vastly increased processability and control over a large range of functional organic materials for which few methods exist to effectively fabricate films with nanoscale features.
有大量的糖尿病患者,对他们来说,简单的呼气测试来确定血糖异常将被认为优于目前的标准血液测试。开发一种非侵入性的血糖监测方法,反映痛苦的血液测试的准确性,不仅将彻底改变糖尿病患者的生活,也将改变监测他们健康的医生的生活。目前作为标准监测方法的痛苦血液测试潜在地昂贵,而且它还阻碍了对血糖的定期监测--通常会产生危险的后果。对于没有意识到低血糖的糖尿病患者来说,这尤其危险,在这种情况下,只有血糖测试会提醒患者注意危险的低血糖水平,这可能会导致昏迷甚至死亡。这项工作将开发气体传感器,用于检测呼气中的挥发性有机化合物(VOCs),作为体内过程的生物标志物,特别是糖尿病患者特有的那些过程。气体传感器包括由共振红外、基质辅助脉冲激光蒸发(RIR-Maple)沉积的有机薄膜。RIR-Maple极大地提高了可加工性和对多种功能有机材料的控制,目前几乎没有方法可以有效地制备具有纳米级特征的薄膜。

项目成果

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Adrienne Stiff-Roberts其他文献

Effect of amino-oligophenylenes on the properties of molybdenum disulfide metal-organic frameworks: Rapid catalytic reduction of nitrophenol in water
氨基低聚亚苯基对二硫化钼金属有机骨架性能的影响:水中硝基酚的快速催化还原
  • DOI:
    10.1016/j.molliq.2025.126906
  • 发表时间:
    2025-03-15
  • 期刊:
  • 影响因子:
    5.200
  • 作者:
    Oluwatosin Folorunsho;Justin Lin;Joshua O. Ayeni;Adrienne Stiff-Roberts;Ufana Riaz;Darlene K. Taylor
  • 通讯作者:
    Darlene K. Taylor

Adrienne Stiff-Roberts的其他文献

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{{ truncateString('Adrienne Stiff-Roberts', 18)}}的其他基金

BRITE Fellow: Semiconductor Evolution via Manufacturing Innovation (SEMI)
BRITE 院士:通过制造创新实现半导体演进 (SEMI)
  • 批准号:
    2227551
  • 财政年份:
    2023
  • 资助金额:
    $ 5万
  • 项目类别:
    Standard Grant
Collaborative Research: Processing Films from Multi-Functional Polymer Dispersion Blends
合作研究:用多功能聚合物分散体共混物加工薄膜
  • 批准号:
    1727572
  • 财政年份:
    2017
  • 资助金额:
    $ 5万
  • 项目类别:
    Standard Grant
NSF/Sandia: Collaborative Research: Hybrid Integration of Nano-Scale Quantum Dots with Micron-Scale Photonic Crystal Cavities for Infrared Sensors
NSF/桑迪亚:合作研究:用于红外传感器的纳米级量子点与微米级光子晶体腔的混合集成
  • 批准号:
    0625099
  • 财政年份:
    2006
  • 资助金额:
    $ 5万
  • 项目类别:
    Standard Grant
CAREER: Hybrid Nanomaterials for Multi-Functional Sensors - Synthesis and Characterization of Nanocomposite Thin-Films for Device Applications
职业:用于多功能传感器的混合纳米材料 - 用于设备应用的纳米复合薄膜的合成和表征
  • 批准号:
    0547273
  • 财政年份:
    2006
  • 资助金额:
    $ 5万
  • 项目类别:
    Standard Grant

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Biogenic Volatile Organic Compound (VOC) Emissions from Managed Landscapes and Their Contribution to Atmospheric Ozone and Aerosol
管理景观中的生物挥发性有机化合物 (VOC) 排放及其对大气臭氧和气溶胶的贡献
  • 批准号:
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MCA:利用人工智能提高对异质森林景观中生物挥发性有机化合物排放和化学的了解
  • 批准号:
    2322325
  • 财政年份:
    2023
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职业:利用流量调制来改变挥发性有机化合物的测量
  • 批准号:
    2346598
  • 财政年份:
    2023
  • 资助金额:
    $ 5万
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Mechanistic triggers of excessive mucus during lung infections by bacterial volatile organic compounds
细菌挥发性有机化合物肺部感染期间粘液过多的机制触发因素
  • 批准号:
    10666271
  • 财政年份:
    2023
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Exhaled volatile organic compounds, phospho-tau and postoperative delirium
呼出的挥发性有机化合物、磷酸tau和术后谵妄
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  • 财政年份:
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底特律挥发性有机化合物与早产的流行病学研究
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    10700809
  • 财政年份:
    2022
  • 资助金额:
    $ 5万
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Impact of Early-life Exposure to Semi-Volatile Organic Compounds (SVOCs) on Neonatal and Early Childhood Immune Function
生命早期接触半挥发性有机化合物 (SVOC) 对新生儿和幼儿免疫功能的影响
  • 批准号:
    10612458
  • 财政年份:
    2022
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使用新型大环材料增强氯化挥发性有机化合物和 1,4-二恶烷共同污染的地下水的生物修复
  • 批准号:
    10641089
  • 财政年份:
    2022
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    $ 5万
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Indoor-outdoor transfer of volatile organic compounds
挥发性有机化合物的室内外转移
  • 批准号:
    572625-2022
  • 财政年份:
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    $ 5万
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RAPID: Biogenic Volatile Organic Compounds (BVOC) Distributions across the Amazon Basin during the Chemistry of the Amazon-Field Experiment (CAFE) Campaign
RAPID:亚马逊化学现场实验 (CAFE) 活动期间整个亚马逊流域的生物挥发性有机化合物 (BVOC) 分布
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