Planning Grant: I/UCRC for I/UCRC for Instrumentation Development for Security and Resilience: Collaborative Research and Community Outreach within Forensic Science

东北法医研究中心(NFORCE)专注于法医科学和国土安全各个领域的样品制备、分离科学和分析检测的发展和进步。主要目标是从事分析研究，这将影响从案件提交到向调查人员和律师报告分析结果的周转时间。积压的案件往往数以千计，影响着全国的刑事司法系统。调查人员打算开发一种方法，与传统方法相比，这种方法将在一小部分时间内提供高水平的验证性测试。科学家们感兴趣的是加快分析化学中各种样本的分析，但并不是专门用于法医科学和国土安全。NFORCE内开展的项目除了法医学和国土安全外，还可能影响药物发现/开发、石油工业和机场安全等领域。NFORCE打算专注于滥用药物、易燃液体和含能材料的分离科学和质谱学检测方面的进展，主要目标是减少总分析时间，以努力减少全国范围内的案件积压。差示迁移率光谱(DMS)和实时直接分析(DART)等方法是分析方法的例子，它们避免了在检测目标分析物之前进行色谱分离的必要性。研究人员建议通过在学术和工业实验室之间开发合作研究计划来实现这些目标，以开发、优化和验证快速和强大的分析仪器方法。将向参与的犯罪实验室(市、州、联邦或私人)提供经过验证的、高通量的分析方法。传播将通过同行评议的出版物完成，并在地方和国家法医学会议上介绍。科学素质、历史观点和从业人员的知识相结合，将促进法医分析化学领域的知识进步。选定的研究活动将根据I/UCRC伙伴关系的最佳利益进行战略制定和集体决定。这项规划拨款由国家科学基金会和国家司法研究所共同支持。

I/UCRC for Instrumentation Development for Security and ResilienceThe Northeastern Forensic Research Center (NFORCE) focuses on the development and advancement of sample preparation, separation science and analytical detection in a variety of areas of forensic science and homeland security. A primary goal is to engage in analytical research, which will impact the turnaround time from case submission to reporting analytical results to investigators and attorneys. Case backlogs, often numbering in the thousands, affect the criminal justice system nationwide. The investigators intend to develop methods which will provide a high level of confirmatory testing in a fraction of the time when compared to traditional approaches. Scientists are interested in speeding up the analysis of a wide variety of samples within analytical chemistry but not specifically for the forensic sciences and homeland security. The projects undertaken within NFORCE would potentially impact areas of drug discovery/development, the petroleum industry and airport security in addition to forensic science and homeland security. NFORCE intends to focus on advances in separation science and mass spectrometric detection for drugs of abuse, ignitable liquids and energetic materials with the primary goal of decreasing the total analysis time in an effort to reduce the case backlogs nationwide. Methods such as differential mobility spectrometry (DMS) and direct analysis in real time (DART) are examples of analytical approaches, which avoid the necessity for chromatographic separation prior to the detection of targeted analytes. The investigators propose to accomplish these goals by developing collaborative research programs between academic and industrial laboratories for the development, optimization and validation of rapid and robust instrumental methods of analysis. Validated, high throughput, analytical methods will be made available to participating crime laboratories (city, state, federal or private). Dissemination will be accomplished through peer-reviewed publications and presented at local and national forensic science conferences. The combination of scientific quality, historical perspective and knowledge of the practitioners will advance knowledge within forensic analytical chemistry. The selected research activities will be strategized and decided upon collectively in the best interests of the I/UCRC partnership.This planning grant is jointly supported by NSF and the National Institute of Justice.