Planning Grant: I/UCRC for I/UCRC for Instrumentation Development for Security and Resilience: Collaborative Research and Community Outreach within Forensic Science

I/UCRC用于安全和弹性仪器开发东北法医研究中心（NFORCE）专注于法医科学和国土安全各个领域的样品制备，分离科学和分析检测的发展和进步。主要目标是从事分析研究，这将影响从案件提交到向调查人员和律师报告分析结果的周转时间。积压的案件往往数以千计，影响到全国的刑事司法系统。研究人员打算开发出一种方法，与传统方法相比，该方法将在一小部分时间内提供高水平的确证性测试。科学家们对加速分析化学中各种样品的分析感兴趣，但不是专门用于法医科学和国土安全。除了法医学和国土安全之外，在NFORCE内开展的项目还可能影响药物发现/开发、石油工业和机场安全等领域。NFORCE计划侧重于滥用药物、易燃液体和高能材料的分离科学和质谱检测方面的进展，主要目标是减少总分析时间，以减少全国积压的案件。诸如差示迁移率光谱法（DMS）和真实的实时直接分析（DART）的方法是分析方法的实例，其避免了在检测目标分析物之前进行色谱分离的必要性。研究人员建议通过开发学术和工业实验室之间的合作研究计划来实现这些目标，以开发，优化和验证快速和强大的仪器分析方法。将向参与的犯罪实验室（城市、州、联邦或私人）提供经过验证的高通量分析方法。将通过同行审查的出版物进行传播，并在地方和国家法医学会议上介绍。科学素质，历史观点和从业人员的知识相结合，将推动法医分析化学知识的发展。选定的研究活动将制定战略，并在I/UCRC合作伙伴关系的最佳利益集体决定。该规划赠款由NSF和国家司法研究所共同支持。

I/UCRC for Instrumentation Development for Security and ResilienceThe Northeastern Forensic Research Center (NFORCE) focuses on the development and advancement of sample preparation, separation science and analytical detection in a variety of areas of forensic science and homeland security. A primary goal is to engage in analytical research, which will impact the turnaround time from case submission to reporting analytical results to investigators and attorneys. Case backlogs, often numbering in the thousands, affect the criminal justice system nationwide. The investigators intend to develop methods which will provide a high level of confirmatory testing in a fraction of the time when compared to traditional approaches. Scientists are interested in speeding up the analysis of a wide variety of samples within analytical chemistry but not specifically for the forensic sciences and homeland security. The projects undertaken within NFORCE would potentially impact areas of drug discovery/development, the petroleum industry and airport security in addition to forensic science and homeland security. NFORCE intends to focus on advances in separation science and mass spectrometric detection for drugs of abuse, ignitable liquids and energetic materials with the primary goal of decreasing the total analysis time in an effort to reduce the case backlogs nationwide. Methods such as differential mobility spectrometry (DMS) and direct analysis in real time (DART) are examples of analytical approaches, which avoid the necessity for chromatographic separation prior to the detection of targeted analytes. The investigators propose to accomplish these goals by developing collaborative research programs between academic and industrial laboratories for the development, optimization and validation of rapid and robust instrumental methods of analysis. Validated, high throughput, analytical methods will be made available to participating crime laboratories (city, state, federal or private). Dissemination will be accomplished through peer-reviewed publications and presented at local and national forensic science conferences. The combination of scientific quality, historical perspective and knowledge of the practitioners will advance knowledge within forensic analytical chemistry. The selected research activities will be strategized and decided upon collectively in the best interests of the I/UCRC partnership.This planning grant is jointly supported by NSF and the National Institute of Justice.