Planning Grant: I/UCRC for I/UCRC for Instrumentation Development for Security and Resilience: Collaborative Research and Community Outreach within Forensic Science

规划拨款：I/UCRC for I/UCRC 用于安全和弹性仪器开发：法证科学领域的合作研究和社区外展

• 批准号: 1464524
• 负责人: Adam Hall
• 金额: $ 1.15万
• 依托单位: Northeastern University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-04-15 至 2017-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1464524&HistoricalAwards=false
• 关键词: Planning; Grant; UCRC; Instrumentation; Development

I/UCRC for Instrumentation Development for Security and ResilienceThe Northeastern Forensic Research Center (NFORCE) focuses on the development and advancement of sample preparation, separation science and analytical detection in a variety of areas of forensic science and homeland security. A primary goal is to engage in analytical research, which will impact the turnaround time from case submission to reporting analytical results to investigators and attorneys. Case backlogs, often numbering in the thousands, affect the criminal justice system nationwide. The investigators intend to develop methods which will provide a high level of confirmatory testing in a fraction of the time when compared to traditional approaches. Scientists are interested in speeding up the analysis of a wide variety of samples within analytical chemistry but not specifically for the forensic sciences and homeland security. The projects undertaken within NFORCE would potentially impact areas of drug discovery/development, the petroleum industry and airport security in addition to forensic science and homeland security. NFORCE intends to focus on advances in separation science and mass spectrometric detection for drugs of abuse, ignitable liquids and energetic materials with the primary goal of decreasing the total analysis time in an effort to reduce the case backlogs nationwide. Methods such as differential mobility spectrometry (DMS) and direct analysis in real time (DART) are examples of analytical approaches, which avoid the necessity for chromatographic separation prior to the detection of targeted analytes. The investigators propose to accomplish these goals by developing collaborative research programs between academic and industrial laboratories for the development, optimization and validation of rapid and robust instrumental methods of analysis. Validated, high throughput, analytical methods will be made available to participating crime laboratories (city, state, federal or private). Dissemination will be accomplished through peer-reviewed publications and presented at local and national forensic science conferences. The combination of scientific quality, historical perspective and knowledge of the practitioners will advance knowledge within forensic analytical chemistry. The selected research activities will be strategized and decided upon collectively in the best interests of the I/UCRC partnership.This planning grant is jointly supported by NSF and the National Institute of Justice.

东北法医研究中心（NFORCE）专注于在法医科学和国土安全的各个领域开发和推进样品制备、分离科学和分析检测。主要目标是从事分析研究，这将影响从案件提交到向调查人员和律师报告分析结果的周转时间。积压的案件往往多达数千件，影响着全国的刑事司法系统。研究人员打算开发一种方法，与传统方法相比，它将在一小部分时间内提供高水平的验证性测试。科学家们对加速分析化学中各种样品的分析感兴趣，但不是专门针对法医科学和国土安全。在NFORCE范围内开展的项目除了法医学和国土安全外，还可能影响药物发现/开发、石油工业和机场安全等领域。NFORCE计划将重点放在分离科学和质谱检测滥用药物、可燃液体和高能物质方面的进展上，主要目标是减少总分析时间，以减少全国范围内的案件积压。差分迁移率光谱法（DMS）和实时直接分析（DART）等方法是分析方法的例子，它们避免了在检测目标分析物之前进行色谱分离的必要性。研究人员建议通过发展学术和工业实验室之间的合作研究计划来实现这些目标，以开发，优化和验证快速和强大的仪器分析方法。经过验证的高通量分析方法将提供给参与的犯罪实验室（城市、州、联邦或私人）。将通过同行评议的出版物进行传播，并在地方和国家法医学会议上发表。科学素质，历史观点和从业者的知识的结合将推进法医分析化学的知识。选定的研究活动将根据研究所/UCRC伙伴关系的最佳利益集体制定战略和决定。这项计划拨款是由美国国家科学基金会和国家司法研究所共同支持的。