Chemical Transformations of Engineered Nanomaterials in the Environment: Fundamental Studies on Plant-Nanomaterial Interactions

环境中工程纳米材料的化学转化：植物-纳米材料相互作用的基础研究

• 批准号: 1506295
• 负责人: Diana Aga
• 金额: $ 46.7万
• 依托单位: SUNY at Buffalo
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-01 至 2019-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1506295&HistoricalAwards=false
• 关键词: Chemical; Transformations; Engineered; Nanomaterials; Environment

With this award, the Environmental Chemical Sciences Program of the Division of Chemistry is funding Professor Diana Aga and Professor Mary A Bisson of the University at Buffalo to investigate the influence of plants on the surface chemistry, fate and toxicity of engineered nanomaterials (ENMs) that are becoming widely used in many industrial, agricultural and consumer products. Plants are among the organisms that will be directly impacted by ENMs entering the environment, therefore an improved understanding of the uptake mechanisms and translocation of ENMs by plants is needed to facilitate the assessment of potential risks associated with environmental contamination by ENMs. The broader impacts of this work include the generation of fundamental knowledge that is critical in developing new regulations to minimize the negative impacts of ENMs, and in promoting compatibility between environmental safety and nanotechnology. Experiments in environmental science are being developed for a science summer camp geared toward middle school children who are disabled and/or economically disadvantaged. The research team is also introducing educational materials to area high school teachers on the applications and implications of nanotechnology that can be incorporated into the high school science curriculum.To achieve these goals, silver nanoparticles (AgNPs) are used as model ENM and Arabidopsis thaliana serves as the model plant species in the series of experiments that are being performed to elucidate the mechanisms of internalization and transformation of AgNPs in plants. This research identifies important interactions between AgNPs and natural organic compounds in plant root exudates that result in surface modifications and changes in the speciation of ENMs. The composition of root exudates from Arabidopsis thaliana, and the changes that occur when plant is treated with AgNPs are being characterized using Fourier transform ion cyclotron resonance mass spectrometry. Wild type and mutant species Arabidopsis are used to determine the role of endocytosis mechanism and metal transporters in the uptake of ENMs. The localization and speciation of Ag in the plant cells are being determined by X-ray absorption fine structure spectroscopy and time of flight secondary ion mass spectrometry.

通过该奖项，化学系的环境化学科学计划是戴安娜·阿加（Diana Aga）教授和布法罗大学的玛丽教授玛丽（Mary a Mary），以调查植物对工程纳米材料（ENM）表面化学，命运和毒性的影响，这些影响在许多工业，农业，农业和消费产品中广泛使用。 植物是将直接受到进入环境的ENM影响的生物之一，因此需要对植物的摄取机制和ENM对ENM的易位进行改进，以促进评估ENM与环境污染相关的潜在风险。 这项工作的更广泛的影响包括基本知识的产生，这对于制定新法规至关重要，以最大程度地减少ENM的负面影响，以及促进环境安全与纳米技术之间的兼容性。环境科学的实验正在为一个针对残疾和/或经济不利的中学儿童的科学夏令营开发。研究团队还向地区高中教师介绍了有关纳米技术的应用和含义，可以将纳米技术的应用和含义纳入高中科学课程中。为了实现这些目标，银纳米粒子（AGNP）用作模型和拟南芥thaliana thaliana thaliana thaliana thaliana thaliana thaliana the nornertions and Internals and Internals and Elucity and Incited of Unuc的模型工厂中的模型，并将其作为模型。 这项研究确定了植物根部渗出剂中AGNP与天然有机化合物之间的重要相互作用，从而导致表面修饰和ENM形成的变化。根部从拟南芥中渗出的根源，使用傅立叶转化离子回旋共振质谱法表征了植物处理时发生的变化。野生型和突变物种拟南芥用于确定内吞作用机理和金属转运蛋白在ENM摄取中的作用。 Ag在植物细胞中的定位和形成是通过X射线吸收细胞光谱和飞行次级离子质谱的时间来确定的。