RAPID: Collaborative Research: Survival of Ebolavirus in the Water Environment: Surrogate Development and Disinfection Effectiveness
RAPID:合作研究:埃博拉病毒在水环境中的生存:替代品开发和消毒效果
基本信息
- 批准号:1508415
- 负责人:
- 金额:$ 11万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2014
- 资助国家:美国
- 起止时间:2014-12-15 至 2016-11-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
CBET 1508415BibbyCBET 1507285HaasRAPID: Collaborative Research: Survival of Ebola virus in the Water Environment: Surrogate Development and Disinfection EffectivenessLittle is known about the fate of Ebola virus and its survival in the environment. Infection in primates has been observed from non-direct contact, raising further the possibility of an environmental infection route. As an initial phase of this RAPID, Ebola virus surrogates, based upon the published data of Ebola virus survival in liquid media, will be developed. Second, the survival of these surrogates will be evaluated in environmental waters (including water and wastewater) and in the presence of water and wastewater disinfectants. This work will be valuable to the broader environmental, public health, and risk assessment communities by providing access to realistic surrogates with which studies (e.g. aerosol and fomite survival studies) may be conducted. The proposed RAPID mechanism is appropriate to inform proper waste handling in a timely manner. This work will also serve to mobilize and inform a response to proper waste handling. Given limited BSL4 access, this approach is the most reasonable response in the near term to inform Ebola virus survival in the water environment, and subsequent risk assessment. Experimental work on this project will be conducted at the University of Pittsburgh. Data and statistical analysis will be conducted at Drexel University. The proposed research will benefit society through informing proper handling of Ebola virus contaminated waste. The proposed work will be disseminated broadly through journal publications and conference proceedings. The proposed research will fill in an existing knowledge gap in the survival and proper handling of Ebola virus contaminated waste. This research will also develop and verify surrogates that may be used by the broader environmental engineering and public health research communities for Ebola virus survival studies.
CBET 1508415 Bibby CBET 1507285 HaasRAPID:合作研究:埃博拉病毒在水环境中的生存:替代发展和消毒效果对埃博拉病毒的命运及其在环境中的生存知之甚少。在灵长类动物中观察到非直接接触感染,进一步增加了环境感染途径的可能性。作为这一快速行动的初始阶段,将根据已公布的埃博拉病毒在液体介质中存活的数据开发埃博拉病毒替代品。其次,将在环境水域(包括水和废水)以及在水和废水消毒剂存在的情况下评估这些替代品的生存情况。这项工作将对更广泛的环境、公共卫生和风险评估社区有价值,因为它提供了进行研究(例如气雾剂和甲壳虫生存研究)的现实替代品。拟议的快速机制适用于及时通知适当的废物处理。这项工作还将有助于动员和通报对适当废物处理的反应。鉴于BSL4获得的机会有限,这种方法是近期最合理的应对措施,可以告知埃博拉病毒在水环境中的生存情况,以及随后的风险评估。该项目的实验工作将在匹兹堡大学进行。数据和统计分析将在德雷塞尔大学进行。这项拟议的研究将通过正确处理受埃博拉病毒污染的废物来造福社会。拟议的工作将通过期刊出版物和会议记录广泛传播。拟议的研究将填补在埃博拉病毒污染废物的生存和适当处理方面的现有知识空白。这项研究还将开发和验证可供更广泛的环境工程和公共卫生研究社区用于埃博拉病毒生存研究的替代品。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Kyle Bibby其他文献
A highly prevalent and specific cryptic plasmid pBI143 for human fecal pollution tracking in a subtropical urban river
一种用于亚热带城市河流中人类粪便污染追踪的高流行且特异性的隐蔽质粒pBI143
- DOI:
10.1016/j.watres.2024.122992 - 发表时间:
2025-04-01 - 期刊:
- 影响因子:12.400
- 作者:
Yawen Liu;Wendy J.M. Smith;Metasebia Gebrewold;Rory Verhagen;Stephen Cook;Stuart L. Simpson;Bethany Oceguera Johnson;Kyle Bibby;Warish Ahmed - 通讯作者:
Warish Ahmed
Metagenomics and the development of viral water quality tools
宏基因组学与病毒水质工具的开发
- DOI:
10.1038/s41545-019-0032-3 - 发表时间:
2019-03-04 - 期刊:
- 影响因子:11.400
- 作者:
Kyle Bibby;Katherine Crank;Justin Greaves;Xiang Li;Zhenyu Wu;Ibrahim A. Hamza;Elyse Stachler - 通讯作者:
Elyse Stachler
Temporal, spatial, and methodological considerations in evaluating the viability of measles wastewater surveillance
评估麻疹废水监测可行性的时间、空间和方法学考虑因素
- DOI:
10.1016/j.scitotenv.2024.178141 - 发表时间:
2025-01-10 - 期刊:
- 影响因子:8.000
- 作者:
William Chen;Kyle Bibby - 通讯作者:
Kyle Bibby
Evaluating Nanotrap Microbiome Particles as A Wastewater Viral Concentration Method
- DOI:
10.1007/s12560-024-09628-w - 发表时间:
2025-01-04 - 期刊:
- 影响因子:2.700
- 作者:
Marlee Shaffer;Devin North;Kyle Bibby - 通讯作者:
Kyle Bibby
Environmental DNA (eDNA) removal rates in streams differ by particle size under varying substrate and light conditions
在不同的基质和光照条件下,溪流中环境 DNA(eDNA)的去除率因颗粒大小而异。
- DOI:
10.1016/j.scitotenv.2023.166469 - 发表时间:
2023-12-10 - 期刊:
- 影响因子:8.000
- 作者:
Elise D. Snyder;Jennifer L. Tank;Pedro F.P. Brandão-Dias;Kyle Bibby;Arial J. Shogren;Aaron W. Bivins;Brett Peters;Erik M. Curtis;Diogo Bolster;Scott P. Egan;Gary A. Lamberti - 通讯作者:
Gary A. Lamberti
Kyle Bibby的其他文献
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{{ truncateString('Kyle Bibby', 18)}}的其他基金
2022 Microbiology of the Built Environment GRC & GRS
2022年建筑环境GRC微生物学
- 批准号:
2225710 - 财政年份:2022
- 资助金额:
$ 11万 - 项目类别:
Standard Grant
RCN: Wastewater Surveillance for SARS-CoV-2 and Emerging Public Health Threats
RCN:针对 SARS-CoV-2 和新出现的公共卫生威胁的废水监测
- 批准号:
2202361 - 财政年份:2022
- 资助金额:
$ 11万 - 项目类别:
Standard Grant
Collaborative Research: RAPID: Wastewater Informed Epidemiological Monitoring of SARS-CoV-2
合作研究:RAPID:废水知情的 SARS-CoV-2 流行病学监测
- 批准号:
2027752 - 财政年份:2020
- 资助金额:
$ 11万 - 项目类别:
Standard Grant
EAGER: Infectious Norovirus Persistence in Water
EAGER:传染性诺如病毒在水中的持久性
- 批准号:
2006326 - 财政年份:2020
- 资助金额:
$ 11万 - 项目类别:
Standard Grant
EAGER: RCN: Wastewater Surveillance of SARS-CoV-2
EAGER:RCN:SARS-CoV-2 废水监测
- 批准号:
2038087 - 财政年份:2020
- 资助金额:
$ 11万 - 项目类别:
Standard Grant
CAREER: Quantitative Viral Metagenomics for Water Quality Assessment
职业:用于水质评估的定量病毒宏基因组学
- 批准号:
1748019 - 财政年份:2017
- 资助金额:
$ 11万 - 项目类别:
Standard Grant
CAREER: Quantitative Viral Metagenomics for Water Quality Assessment
职业:用于水质评估的定量病毒宏基因组学
- 批准号:
1653356 - 财政年份:2017
- 资助金额:
$ 11万 - 项目类别:
Standard Grant
UNS: Developing Cross-Assembly Phage As A Marker of Human Fecal Pollution in the Environment
UNS:开发交叉组装噬菌体作为环境中人类粪便污染的标志
- 批准号:
1818412 - 财政年份:2017
- 资助金额:
$ 11万 - 项目类别:
Standard Grant
Workshop Proposal: Wastewater Handling in Outbreak Response - Lessons and Research Needs from the 2014/15 Ebola Virus Outbreak
研讨会提案:疫情应对中的废水处理 - 2014/15 埃博拉病毒爆发的经验教训和研究需求
- 批准号:
1612429 - 财政年份:2016
- 资助金额:
$ 11万 - 项目类别:
Standard Grant
UNS: Developing Cross-Assembly Phage As A Marker of Human Fecal Pollution in the Environment
UNS:开发交叉组装噬菌体作为环境中人类粪便污染的标志
- 批准号:
1510925 - 财政年份:2015
- 资助金额:
$ 11万 - 项目类别:
Standard Grant
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