Bilayered and growth factor-loaded composite scaffolds for the guided bi-differentiation of bone marrow stem cells

用于引导骨髓干细胞双分化的双层负载生长因子复合支架

• 批准号: DP0881045
• 负责人: Prof Yin Xiao
• 金额: $ 17.7万
• 依托单位: Queensland University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0881045
• 关键词: Bilayered; growth; factor; loaded; composite

The project will regenerate bone-cartilage (osteochondral) tissues using scaffolds, growth factors, and stem cells in order to repair osteochondral defects. The project will improve the quality of life for ~1.4 million Australians suffering from joint pain and disability due to damage or disease of cartilage and subchondral bone. The project will promote Australia research strength in biomaterials, tissue engineering, and drug delivery. The project will also create research opportunities for PhD students, who will be equipped with interdisciplinary skills.

该项目将利用支架、生长因子和干细胞再生骨软骨（骨软骨）组织，以修复骨软骨缺陷。该项目将改善约 140 万因软骨和软骨下骨损伤或疾病而遭受关节疼痛和残疾的澳大利亚人的生活质量。该项目将提升澳大利亚在生物材料、组织工程和药物输送方面的研究实力。该项目还将为博士生创造研究机会，让他们具备跨学科技能。