Science and Technology Center on Real-Time Functional Imaging (STROBE)

实时功能成像科技中心（STROBE）

• 批准号: 1548924
• 负责人: Margaret Murnane
• 金额: $ 2400万
• 依托单位: University of Colorado at Boulder
• 依托单位国家: 美国
• 项目类别: Cooperative Agreement
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-10-01 至 2026-09-30
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1548924&HistoricalAwards=false
• 关键词: Science; Technology; Center; Real; Time

Understanding the structure and evolution of matter at the nanometer and atomic scales is central for discovery and innovation in science and technology, accelerating advances in materials science, condensed matter physics, chemistry, biology, engineering, geology, and medicine. This Science and Technology Center (STC) aims to advance and integrate different imaging modalities using electron, X-ray, optical, and nano-probe microscopy to collectively tackle major scientific challenges. It brings together an interdisciplinary team from University of Colorado at Boulder; Universities of California at Berkeley, Los Angeles, and Irvine; Florida International University; and Fort Lewis College, in partnership with national laboratories, US industries, and international collaborators.Education and Diversity: This STC develops, implements, assesses, and disseminates new programs to educate a diverse group of students to be innovative and globally competitive in imaging science and technology. It focuses particularly on two signature efforts: (i) new multidisciplinary graduate certificate and degree programs and (ii) multi-year, cross-institutional undergraduate, master's, and Ph.D. degree programs. The center's education activities are designed to realize the following version of the future: K-12 students will apprehend the exciting opportunities of science and engineering careers. Undergraduate students will appreciate the connections between different areas of science and engineering, as well as the relation between these fields and industry. Ph.D. graduates will acquire expertise with depth and breadth to innovate, lead team research, and create new technologies through entrepreneurship.Knowledge Transfer: This STC aims to manifest through national and international leadership in cutting-edge imaging science, highly-needed diverse graduates trained in multidisciplinary science, and a plethora of hybrid/adaptive imaging modalities and tabletop systems, enabling new science to emerge in the upcoming decades, as well as technology transfer to industry and emerging startups. Faster, higher-resolution and more sensitive imaging techniques will benefit a wide range of scientific disciplines as well as various industrial sectors, which can directly translate technological advances to improving the economy and the standard of living.Technical Description of the Center Research:A major goal of this STC is to address key cross-cutting challenges common to all imaging modalities and tackle science grand challenges across different disciplines. When advances in high-speed direct detectors, advanced algorithms, big-data manipulation methods, new light and electron sources (including tabletop coherent X-ray sources), and spectrally/spatially/temporally structured illumination are integrated, they can fundamentally transform imaging science to enable real-time three-dimensional functional imaging. In addition, by combining electron with optical imaging, or coherent X-ray imaging with ultrafast lasers, or coherent infrared spectroscopies with nano-probe imaging, scientists in this center investigate new hybrid and adaptive imaging modalities that far exceed current capabilities. An expected outcome is creation and integration of a new set of powerful and broadly applicable real-time imaging modalities that can image non-crystalline systems and implement dynamic imaging with a large field of view with chemical and magnetic contrast and with atomic/molecular/nanoscale resolution. Each imaging technique will be brought to reach its fundamental limits and integrated in hybrid/adaptive modalities that surpass the sum of the parts.

了解纳米和原子尺度下物质的结构和演化是科学技术发现和创新的核心，加速了材料科学，凝聚态物理，化学，生物学，工程学，地质学和医学的进步。该科学和技术中心（STC）旨在推进和整合使用电子，X射线，光学和纳米探针显微镜的不同成像模式，以共同应对重大科学挑战。它汇集了来自博尔德的科罗拉多大学，伯克利的加州大学，洛杉矶大学和欧文大学，佛罗里达国际大学和刘易斯堡学院的跨学科团队，与国家实验室，美国行业和国际合作者合作。教育和多样性：该STC开发，实施，评估，并传播新的计划，以教育多样化的学生群体在成像科学和技术方面具有创新性和全球竞争力。它特别侧重于两个签名的努力：（一）新的多学科研究生证书和学位课程，（二）多年，跨机构的本科，硕士和博士。学位课程。该中心的教育活动旨在实现未来的以下版本：K-12学生将理解科学和工程职业的令人兴奋的机会。本科生将欣赏科学和工程的不同领域之间的联系，以及这些领域和行业之间的关系。博士毕业生将获得具有深度和广度的专业知识，以创新，领导团队研究，并通过创业创造新技术。知识转移：该STC旨在通过在尖端成像科学方面的国家和国际领导地位，在多学科科学方面训练有素的急需的多样化毕业生，以及过多的混合/自适应成像模式和桌面系统来体现，使新的科学在未来几十年中出现，以及向工业和新兴创业公司的技术转让。更快、更高分辨率和更灵敏的成像技术将使广泛的科学学科以及各个工业部门受益，这可以直接将技术进步转化为提高经济和生活水平。技术描述中心研究：该STC的主要目标是解决所有成像模式共同面临的关键交叉挑战，并解决不同学科的科学重大挑战。当高速直接探测器、先进算法、大数据操作方法、新光源和电子源（包括桌面相干X射线源）以及光谱/空间/时间结构化照明的进步被集成时，它们可以从根本上改变成像科学，实现实时三维功能成像。此外，通过将电子与光学成像相结合，或将相干X射线成像与超快激光相结合，或将相干红外光谱与纳米探针成像相结合，该中心的科学家们研究了远远超过当前能力的新型混合和自适应成像模式。一个预期的结果是创建和集成一套新的强大的和广泛适用的实时成像模式，可以成像非晶体系统，并实现动态成像与化学和磁对比度和原子/分子/纳米级分辨率的大视场。每种成像技术都将达到其基本极限，并集成到混合/自适应模式中，超越各部分的总和。