The Influence of Sleep on Declarative Memory in the First Year of Life

睡眠对生命第​​一年陈述性记忆的影响

• 批准号: 222284150
• 负责人: Professorin Dr. Sabine Seehagen
• 金额: --
• 依托单位: Abteilung Entwicklungspsychologie
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2012
• 资助国家: 德国
• 起止时间: 2011-12-31 至 2014-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/222284150?language=en
• 关键词: Influence; Sleep; Declarative; Memory; First

In adults, it is well established that sleep plays an important role in memory consolidation. Benefits of sleep for memory processing include, for example, the strengthening of existing memories, facilitation of new insights into previously encountered problems, and promotion of knowledge transfer. However, due to the lack of conclusive experimental evidence, it is currently unknown at what point during ontogeny sleep starts to benefit specific memory processes. In two deferred imitation experiments with 6- and 12-month-old infants, the influence of sleep on three fundamental aspects of declarative memory will be investigated: retention of a learning event, flexibility of memory retrieval, and abstraction of knowledge. To assess the effect of sleep on memory, a learning event and a test session will be scheduled around infants natural sleep patterns such that some infants will sleep shortly after learning and some infants will not sleep within four hours after the learning event. It is expected that sleep will facilitate all three aspects of declarative memory. Furthermore, we expect the effect of sleep on memory to be stronger in 12-month-old infants in comparison to 6-month-old infants due to the rapidly maturing sleep architecture during early infancy.

对于成年人来说，睡眠在记忆巩固中起着重要的作用，这是公认的。睡眠对记忆处理的好处包括，例如，加强现有记忆，促进对以前遇到的问题的新见解，以及促进知识转移。然而，由于缺乏确凿的实验证据，目前尚不清楚在个体发育过程中，睡眠在什么时候开始对特定的记忆过程有益。在两项针对6个月和12个月婴儿的延迟模仿实验中，研究了睡眠对陈述性记忆三个基本方面的影响：学习事件的保留、记忆提取的灵活性和知识的抽象。为了评估睡眠对记忆的影响，将围绕婴儿的自然睡眠模式安排一个学习活动和一个测试环节，这样一些婴儿在学习后不久就会睡觉，而一些婴儿在学习后的四个小时内不会睡觉。预计睡眠将促进陈述性记忆的所有三个方面。此外，我们预计12个月大的婴儿睡眠对记忆的影响比6个月大的婴儿更强，因为婴儿早期的睡眠结构迅速成熟。

项目成果

Timely sleep facilitates declarative memory consolidation in infants

• DOI: 10.1073/pnas.1414000112
• 发表时间: 2015-02-03
• 期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
• 影响因子: 11.1
• 作者: Seehagen, Sabine;Konrad, Carolin;Schneider, Silvia
• 通讯作者: Schneider, Silvia