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REU Site: Research and Training in Biochemistry, Biophysics and Biodesign (B3) for Undergraduates

REU Site: Research and Training in Biochemistry, Biophysics and Biodesign (B3) for Undergraduates
REU 网站:本科生生物化学、生物物理学和生物设计 (B3) 的研究和培训
批准号:
1560384
负责人:
David Jeruzalmi
金额:
$31.84万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2016
资助国家:
美国
项目状态:
已结题
起止时间:
2016-09-15 至 2019-12-31

项目摘要

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中文摘要
翻译
位于纽约的纽约城市学院(CCNY)获得了生物化学、生物物理学和生物设计(B3)REU Site奖,该奖项将在2017-2019年夏季支持9名学生为期10周的培训。该项目得到了生物科学局(BIO)的生物基础设施处(DBI)和数学与物理科学局(MPS)的化学处(CHE)的支持。B3研究计划由来自五个不同部门的教师导师组成,他们聚集在新的发现和创新中心(CDI),该中心培育了一个强大的协作环境。该项目的特点是在生物、化学、物理和工程方面为学生提供最先进的研究培训,包括使用核磁共振光谱、X射线结晶学和分子动力学模拟方面的先进技术。为学生提供的令人兴奋的项目涉及信号的结构生物学,DNA损伤修复,仿生组装的工程,以及新型酶的设计。B3-REU将主要培训纽约城市大学(CUNY)系统的CCNY本科生和社区学院的学生,但也将接受其他社区学院或研究机会有限的学校的申请。实验科学将辅以讲习班和研讨会、伦理培训、STEM职业讨论和实地考察,以使学生,特别是那些来自代表不足和服务不足的群体的学生,建立一种科学家的身份,这将激励他们追求更高的科学学位和职业。学生将向项目指导委员会提交申请,并被项目指导委员会录取。预计共有27名学生将接受该项目的培训,这些学生主要来自CCNY和CUNY研究机会有限的学校。该计划将广泛影响三个领域:1)吸引和留住学生,包括代表性不足和经济困难的群体,攻读STEM专业;2)为学生提供生物化学、生物物理学和生物设计方面的多学科培训;3)提高CCNY和CUNY STEM学科的保留率和毕业率。学生将学习研究是如何进行的,许多人将在科学会议上展示他们的工作成果。由生物基础设施部(生物科学局)资助的所有REU项目都将使用一个通用的基于网络的评估工具来确定培训计划的有效性。项目结束后,将对学生进行跟踪,以确定他们的职业道路。学生将被要求回复通过NSF报告系统发送的自动电子邮件。有关该计划的更多信息,请访问https://www.ccny.cuny.edu/engagement/nsf-reu-summer-program-2017或联系PI(David Jeruzalmi博士,DJ@ccny.cuny.edu)。
英文摘要
The Biochemistry, Biophysics and Biodesign (B3) REU site award to City College of New York (CCNY), located in New York, NY, will support the training of 9 students for 10 weeks during the summers of 2017-2019. This project is supported by the Division of Biological Infrastructure (DBI) in the Directorate for Biological Sciences (BIO) and the Division of Chemistry (CHE)in the Directorate for Mathematics & Physical Sciences (MPS). The B3 research program is comprised of faculty mentors from five different departments housed together in the new Center for Discovery and Innovation (CDI) which fosters a strong collaborative environment. The program features state-of-the-art research training for students at the interface of biology, chemistry, physics, and engineering, including the use of advanced techniques in NMR spectroscopy, X-ray crystallography, and molecular dynamics simulations. Exciting projects available to students address the structural biology of signaling, DNA damage repair, engineering of biomimetic assemblies, and the design of novel enzymes. The B3-REU will primarily train CCNY undergraduates and students from community colleges at the City University of New York (CUNY) system, but will also accept applications from other community colleges or schools with limited opportunities for research. Experimental science will be supplemented with workshops and seminars, ethics training, STEM career discussions, and field trips to enable students, especially those from under-represented and underserved groups, to develop an identity as a scientist that will motivate the pursuit of advanced degrees and careers in science. Students will submit applications to, and be admitted by, the program steering committee.It is anticipated that a total of 27 students, primarily from CCNY and CUNY schools with limited research opportunities, will be trained in the program. The program will broadly impact three areas: 1) attracting and retaining students, including underrepresented and economically disadvantaged groups, to STEM pursuits, 2) providing multi-disciplinary training of students in Biochemistry, Biophysics and Biodesign, and 3) increasing retention and graduation rates in STEM disciplines at CCNY and CUNY. Students will learn how research is conducted, and many will present the results of their work at scientific conferences.A common web-based assessment tool used by all REU programs funded by the Division of Biological Infrastructure (Directorate for Biological Sciences) will be used to determine the effectiveness of the training program. Students will be tracked after the program in order to determine their career paths. Students will be asked to respond to an automatic email sent via the NSF reporting system. More information about the program is available at https://www.ccny.cuny.edu/engagement/nsf-reu-summer-program-2017 or by contacting the PI (Dr. David Jeruzalmi dj@ccny.cuny.edu).
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Molecular machinery of the bacterial nucleotide excision repair pathway
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