DISSERTATION RESEARCH: Relationship between Maternal Social Status, Offspring Health, and Female Dispersal Success in Wild Meerkats

论文研究：野生猫鼬中母亲社会地位、后代健康与雌性扩散成功之间的关系

• 批准号: 1601685
• 负责人: Christine Drea
• 金额: $ 1.91万
• 依托单位: Duke University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-06-01 至 2018-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1601685&HistoricalAwards=false
• 关键词: DISSERTATION; RESEARCH; Relationship; between; Maternal

Many animals leave their birth places as they become adults to avoid competing or mating with relatives. However, traveling to and settling in a new area can be dangerous as animals are exposed to new diseases, predators, and unfriendly neighbors. This project is to identify the qualities that help these animals along the way, and to test whether those that are better able to withstand disease and to cope with stress are more successful. The research team will use sophisticated GPS technology to monitor the health and survival of young female Meerkats in the Kalahari Desert as they move from one social group to another. The project will also train undergraduate students and engage schoolchildren in the research through popular media and the Friends of Kalahari website. In addition to advancing our knowledge of dispersal, the results of this study will inform the ways in which we manage animals in fragmented and changing habitats. In previous work on meerkat societies, the PIs found that dominant females, which are hormonally "masculinized", have the weakest constitutive immune responses of all group members, indicating a cost of androgen exposure in females. Moreover, because androgen concentrations vary with female social status, the PIs found evidence for organizational effects of differential prenatal androgen exposure on the health of juvenile offspring derived from dominant control (DC), subordinate control (SC), and dominant treated (DT) dams receiving an androgen-receptor blocker. Here, the PIs will follow the daughters of DC, SC, and DT dams over the next life-history stage "dispersal" to study the transgenerational effects of maternal social status/prenatal T on offspring dispersal. Using an integrated approach that combines behavioral, hormonal, and immunological analyses with novel global positioning system (GPS) telemetry data, the PIs will chart the health and social trajectories of daughters over successive stages of dispersal (during emigration from the natal group, a transience period, and settlement in a new territory). Specifically, the PIs will (1) determine dominance relationships and identify likely dispersers via regular behavioral observation; (2) fit GPS radio collars to 25 pre-dispersal females and chart their movements on an hourly basis; (3) measure immunocompetence (parasite burden and immune response) and hormone concentrations (androgens and glucocorticoids) in (a) fecal samples (collected prior to, over the course of, and following dispersal) and (b) serum samples (collected pre-dispersal and post-settlement); and (4) evaluate the health and survival of these females in their newly formed groups.

许多动物在成年后离开出生地，以避免与亲戚竞争或交配。然而，旅行和定居在一个新的地区可能是危险的，因为动物暴露于新的疾病，捕食者和不友好的邻居。这个项目是为了确定帮助这些动物沿着的品质，并测试那些能够更好地抵御疾病和科普压力的动物是否更成功。研究小组将使用先进的GPS技术来监测卡拉哈里沙漠中年轻雌性猫鼬的健康和生存，因为它们从一个社会群体转移到另一个社会群体。该项目还将培训本科生，并通过大众媒体和卡拉哈里之友网站让学童参与研究。除了提高我们对扩散的认识外，这项研究的结果还将为我们在破碎和不断变化的栖息地中管理动物的方式提供信息。在先前对猫鼬社会的研究中，PI发现，占主导地位的雌性动物在生殖上“男性化”，在所有群体成员中具有最弱的组成性免疫反应，这表明雌性动物暴露于雄激素的代价。此外，由于雄激素浓度随女性社会地位而变化，PI发现了差异产前雄激素暴露对来自显性对照（DC）、从属对照（SC）和接受雄激素受体阻滞剂的显性治疗（DT）母鼠的幼年后代健康的组织影响的证据。在这里，PI将遵循女儿的DC，SC和DT大坝在下一个生活史阶段的“扩散”，研究跨代的影响，母亲的社会地位/产前T后代扩散。使用一种综合的方法，结合行为，激素和免疫分析与新的全球定位系统（GPS）遥测数据，PI将绘制女儿的健康和社会轨迹在连续阶段的传播（在从纳塔尔组移民，过渡期，并在一个新的领土定居）。具体而言，PI将（1）确定优势关系，并通过定期行为观察识别可能的扩散者;（2）为25只扩散前的雌性动物安装GPS无线电项圈，并以小时为单位绘制它们的运动图;（3）测量免疫活性（寄生虫负荷和免疫反应）和激素浓度（a）粪便样本中的雄激素和糖皮质激素（在分散之前、过程中和之后收集）和（B）血清样品（收集前分散和定居后）;（4）评估这些女性在其新成立的团体的健康和生存。