Collaborative Research: Understanding and Controlling Chemo-Mechanical Properties of Metal Coordinating Polymer and Inorganic Nanoparticle Composites

合作研究：了解和控制金属配位聚合物和无机纳米颗粒复合材料的化学机械性能

• 批准号: 1605943
• 负责人: Niels Holten-Andersen
• 金额: $ 25万
• 依托单位: Massachusetts Institute of Technology
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-01 至 2019-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1605943&HistoricalAwards=false
• 关键词: Collaborative; Research; Understanding; Controlling; Chemo

1605943/1605699Holten-Andersen, Niels/Tracy, Joseph B. Interfaces between metal coordinating proteins and inorganic surfaces have a vital role in the mechanical properties of some of the most remarkable composites found in nature. From the underwater adhesive glues of mussels to the tough shells of nacre, sticky interactions between metal binding proteins and inorganic surfaces have increasingly been found to control their mechanical properties. A simpler, synthetic system, where inorganic nanoparticles serve as dynamic bridges for metal binding polymers, will be investigated to learn principles of composite material design from nature and to apply these principles for engineering new materials with controlled and responsive mechanical properties. Potential applications for these materials include drug delivery, self-healing composites, and 3D printing. The PIs will develop learning modules based on these bio-inspired composites for use in outreach activities to increase public awareness about nanotechnology and to recruit more students into STEM careers.The goal of this project is to utilize bio-inspired metal coordinating polymer-nanoparticle (MCP-NP) composites as model systems for understanding how to engineer novel mechanics via controlled MCP-NP interfacial dynamics. In contrast to previous MCP materials with metal ion crosslinkers, NPs will serve as supramolecular crosslinkers, with a tunable number of ligands bound per NP. Chemical and physical parameters of the system will be adjusted to obtain a fundamental understanding of how molecular interactions at MCP-NP interfaces affect the bulk mechanical properties of MCP-NP composites and to demonstrate control over the mechanical response. In comparison with traditional engineering composites and other composite hydrogels, MCP-NP composites are viscoelastic and have tunable interfacial bonding. Magnetically and optically responsive NPs have been selected to also allow remote heating using light and magnetic fields. This project will provide a deeper understanding of composite interfacial dynamics critical for improved engineering of composite mechanical properties, such as self-healing and tunable fluid-solid transitions. Insights about the relationship between chemistry at MCP-NP interfaces and the mechanical response will be applicable to other composite systems with dynamic interfaces.

1605943/1605699 Holten-Andersen，Niels/Tracy，JosephB。金属协调蛋白和无机表面之间的接口在自然界中一些最引人注目的复合材料的机械性能中具有至关重要的作用。从贻贝的水下粘合剂到NACRE的坚韧壳，越来越多地发现金属结合蛋白和无机表面之间的粘性相互作用可以控制其机械性能。 将研究一个简单，合成的系统，其中无机纳米颗粒是金属结合聚合物的动态桥梁，将研究从自然界学习复合材料设计的原理，并将这些原理应用于具有控制和响应机械性能的新材料。 这些材料的潜在应用包括药物输送，自我修复复合材料和3D打印。 The PIs will develop learning modules based on these bio-inspired composites for use in outreach activities to increase public awareness about nanotechnology and to recruit more students into STEM careers.The goal of this project is to utilize bio-inspired metal coordinating polymer-nanoparticle (MCP-NP) composites as model systems for understanding how to engineer novel mechanics via controlled MCP-NP interfacial dynamics. 与以前具有金属离子交联的MCP材料相反，NP将用作超分子交联剂，每个NP都有可调数的配体。 将调整系统的化学和物理参数，以获得对MCP-NP接口的分子相互作用如何影响MCP-NP复合材料的整体机械性能的基本了解，并证明对机械响应的控制。 与传统的工程复合材料和其他复合水凝胶相比，MCP-NP复合材料是粘弹性的，具有可调的界面键合。 已经选择了磁性和光学响应的​​NP，还可以使用光和磁场进行远程加热。 该项目将对改进复合机械性能的工程（例如自我修复和可调液 - 固定过渡跃迁）的工程至关重要的复合界面动力学有更深入的了解。 关于MCP-NP接口和机械响应化学之间关系的洞察力将适用于具有动态接口的其他复合系统。