Expanding the Scope and Enabling Potential of Direct Arylation Polymerization (DArP)

化学系的大分子、超分子和纳米化学项目支持巴里C教授的项目。汤普森 汤普森教授是南加州大学（USC）化学系的教员。 汤普森教授的研究开发了新的合成方法来制备共轭聚合物。 共轭聚合物已经成为有机电子学的一个非常有吸引力的平台，特别是用于太阳能电池和发光二极管等应用。 目前制造这些装置的合成方法是困难的。 这些反应通常需要高度反应性和易燃的试剂进行制备。这些主要的化学物质也将单体的类型限制在一个狭窄的组中，进一步限制了聚合物性能的范围。本研究描述了一种策略，以开发新的合成技术，使聚合物，直接芳基化聚合（DArP），成为一个强大的，广泛的，并使平台的共轭聚合物的合成。汤普森教授的假设是，通过仔细控制反应参数和添加剂，DArP可以与各种单体体系广泛相容，并且可以表现出比传统的共轭聚合物合成方法更好的选择性。该研究项目还为共轭聚合物的合成提供了一条更加绿色和可持续的路线。 该研究通过南加州大学喜瑞都学院暑期实习计划为社区大学学生提供培训。DArP的优化和由DArP制备的聚合物的最终规模化提供了一种显著更经济和环境友好的方法来合成用于太阳能电池应用的聚合物。 这项研究描述了汤普森教授？的战略发展直接芳基化聚合（DArP）成为一个强大的，广泛的，并使共轭聚合物的合成平台。这项工作的动机是基于有限的共轭聚合物合成方法。虽然DArP可以有吸引力地绕过金属化要求，但它目前在官能团耐受性和缺陷最小化方面落后于最先进的方法，如Stille方法，并且在控制聚合物生长方面落后于Kumada催化剂转移缩聚（KTCP）反应。 因此，本研究的主要目标是：1.建立一个广泛适用的直接芳基化聚合平台，是通用的和强大的，2。开发氧化直接芳基化聚合反应，用于生成聚合物，而无需预活化单体，和3。改进DArP平台，以增强对聚合物生长的控制以及与更丰富的金属催化剂的兼容性。 汤普森教授的方法来实现这些目标是一个假设驱动的研究的基础上有前途的观察小分子直接芳基化。 这种方法不仅能够扩展小分子化学，而且能够通过简单、模块化的反应参数控制来适应和开发新的聚合物化学。

The Macromolecular, Supramolecular and Nanochemistry Program of the Chemistry Division supports the project by Professor Barry C. Thompson. Professor Thompson is a faculty member in the Department of Chemistry at the University of Southern California (USC). Professor Thompson's research develops new synthetic methods to prepare conjugated polymers. Conjugated polymers have emerged as a highly attractive platform for organic electronics and specifically for applications such as solar cells and light emitting diodes. The current synthetic methods of making these devices are difficult. These reactions typically require highly reactive and flammable reagents for preparation. These prevailing chemistries also limit the type of monomers to a narrow group, further limiting the range of polymer properties. This research describes a strategy to develop the new synthetic technique for making polymers, Direct Arylation Polymerization (DArP), into a robust, broad-reaching, and enabling platform for the synthesis of conjugated polymers. Professor Thompson?s hypothesis is that through careful control of reaction parameters and additives, DArP can be made to be broadly compatible with a variety of monomer systems and can exhibit selectivity better than traditional methods of conjugated polymer synthesis. The research project also offers a significantly more green and sustainable route to conjugated polymer synthesis. The research provides training for community college students through the USC-Cerritos College summer internship program. Optimization of DArP and the ultimate scale-up of polymers made by DArP provides a significantly more economical and environmentally friendly way to synthesize polymers for solar cell applications. This research describes Professor Thompson?s strategy to develop Direct Arylation Polymerization (DArP) into a robust, broad-reaching, and enabling platform for the synthesis of conjugated polymers. Motivation for this work is based on the limited methods for conjugated polymer synthesis. While DArP can attractively bypass metalation requirements, it currently lags behind state-of-the-art methods like Stille methods in terms of functional group tolerance and minimization of defects andas Kumada catalyst-transfer polycondensation (KTCP) reactions in terms of control over polymer growth. As a result, the major objectives of this work are to: 1. Establish a broadly applicable direct arylation polymerization platform that is both versatile and robust, 2. Develop oxidative direct arylation polymerization for the generation of polymers without preactivation of the monomers, and 3. Refine the DArP platform for enhanced control over polymer growth and compatibility with more abundant metal catalysts. Professor Thompson?s approach toward achieving these objectives is a hypothesis driven study based on promising observations in small molecule direct arylation. This methods has theability to not just extend small molecule chemistry but to adapt and develop new polymer chemistry through simple, modular control of reaction parameters.