MRI: Acquisition of an upgraded radio frequency console, a broadband nitrogen-cooled probe and an autosampler for a 400 MHz nuclear magnetic resonance (NMR) spectrometer

在主要研究仪器项目（MRI）的奖励和化学研究仪器项目（CRIF）的支持下，来自Susquehanna大学的William Dougherty教授及其同事Geneive Henry和Elizabeth Valentin升级了400 MHz核磁共振（NMR）光谱仪，为其配备了新的射频控制台，能够在-100到+150摄氏度之间工作的宽带探头和24位自动进样器。升级后的光谱仪电子设备允许在各种领域进行研究，例如那些加速具有重大经济意义的化学反应的领域，以及那些允许研究生物相关物种的领域。总的来说，核磁共振波谱学是化学家用来阐明分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，以及研究溶液或固体状态下分子之间相互作用的动力学。这些核磁共振研究的结果在合成有机/无机化学、材料化学和生物化学等领域具有重要影响。采集到的探头可同时作为宽带和高场探头，从而提高了灵敏度。该仪器是本科学生通过独立学生研究和传统学术课程进行教学和研究的一个组成部分。该奖项旨在加强各级的研究和教育，特别是在以下领域：(a)了解化学结构对过渡金属配合物氧化还原性质的影响；(b)研究具有立体体积的三吡唑硼酸酯配体的第一排过渡金属配合物的氧化还原特性；(c)分离和光谱表征生长在宾夕法尼亚州的Carex（草类植物或莎草）和Hypericum（草本灌木）的天然产物。

With this award from the Major Research Instrumentation Program (MRI) and support from the Chemistry Research Instrumentation Program (CRIF), Professor William Dougherty from Susquehanna University and colleagues Geneive Henry and Elizabeth Valentin have upgraded a 400 MHz Nuclear Magnetic Resonance (NMR) spectrometer by equipping it with a new radio frequency console, a broadband probe capable of operating between -100 and +150 degrees Centigrade and a 24-position autosampler. The upgraded electronics for the spectrometer allows research in a variety of fields such as those that accelerate chemical reactions of significant economic importance, as well as those that allow study of biologically relevant species. In general, NMR spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. The results from these NMR studies have an impact in synthetic organic/inorganic chemistry, materials chemistry and biochemistry. The acquired probe acts both as a broadband and high-field probe which increases sensitivity. This instrument is an integral part of teaching as well as research performed by undergraduate students via independent student research and traditional academic coursework.The award is aimed at enhancing research and education at all levels, especially in areas such as (a) understanding the influence chemical structure has on the redox properties of transition metal complexes; (b) studying the redox properties of first row transition metal complexes bearing sterically bulky trispyrazolylborate ligands and (c) isolating and spectroscopically characterizing natural products from Carex (grassy plants or sedge) and Hypericum species (herbaceous shrubs) growing in Pennsylvania.