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Barnacle Adhesion and Adhesives: Biomechanical, Molecular and Cellular Aspects

Barnacle Adhesion and Adhesives: Biomechanical, Molecular and Cellular Aspects
藤壶附着力和粘合剂:生物力学、分子和细胞方面
批准号:
9117220
负责人:
William Dougherty
金额:
$25.0万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
1992
资助国家:
美国
项目状态:
已结题
起止时间:
1992-09-01 至 1996-08-31

项目摘要

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中文摘要
翻译
胶粘剂在人类日常生活中的价值和应用几乎是无限的。与大多数人造粘合剂不同,藤壶合成和分泌的生物粘合剂在水下形成粘合。这一特性在牙科、医疗、海水养殖、建筑和建筑以及其他工业应用中可能被证明是有用的。我们在实验室的海水养殖中采集了当地藤壶的粘性分泌物样本。标准和创新附着力测试的应用将提高我们对各种基材界面上发生的机械和化学相互作用以及水下粘合分泌物的了解。藤壶粘附性分泌物的电泳层析组分,具有粘附性。对藤壶的显微研究将精确定位合成和分泌黏附大分子的细胞。大分子的分离和提纯将使这些重要材料的进一步研究和应用成为可能。在未来,基因工程方法将生产足够数量的合成藤壶生物粘合剂,以满足牙科、医疗、家庭和工业需求,这是合理的。此外,在确定了藤壶粘附性的化学基础后,可以合成出粘附胶。将这种防粘剂加入到海洋表面涂料中,可以最大限度地减少环境污染和藤壶对世界船民、托运人和海军的经济影响。
英文摘要
The value and applications of adhesives are almost limitless in daily human existence. The bioadhesives synthesized and secreted by barnacles, unlike most man-made adhesives, forms bonds under water. This characteristic may prove useful in dental, medical, mariculture, building and construction, and other industrial applications. We have collected samples of an adhesive secretion from local barnacles held in sea water culture in our laboratory. The application of both standard and innovative adhesion tests will advance our knowledge of the mechanical and chemical interactions that occur at the interface of various substrates and this adhesive secretion under water. Electrophoretic and chromatographic components of the barnacle adhesive secretion that exhibit adhesive properties. Microscopic studies of barnacles will pinpoint the cells that synthesize and secrete adhesive macromolecules. Isolation and purification of the macromolecules will allow additional studies and applications of these important materials. In the future, it is reasonable to expect that genetic engineering methods will produce synthetic barnacle bioadhesives in sufficient quantities to satisfy dental, medical, household, and industrial needs. Moreover, after determining the chemical basis of adhesion of barnacle "glue", could be synthesized. The incorporation of such anti-adhesives into marine surface coatings could minimize environmental pollution and the economic impact of barnacles on the boaters, shippers, and navies of the world.
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MRI: Track 1 Acquisition of a Single-Crystal X-ray Diffractometer to Support Primarily Undergraduate Research in the Greater Susquehanna Valley
  • 批准号:
    2320461
  • 项目类别:
    Standard Grant
  • 资助金额:
    $20.02万
  • 财政年份:
    2023
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    William Dougherty
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MRI: Acquisition of an upgraded radio frequency console, a broadband nitrogen-cooled probe and an autosampler for a 400 MHz nuclear magnetic resonance (NMR) spectrometer
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Identification and Analysis of a Potyviral RNA-dependent RNA-polymerase
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    8902610
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  • 财政年份:
    1989
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  • 依托单位:
Synthesis and Activity of the Large Nuclear Inclusion Protein of Tobacco Etch Virus
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    8796226
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    $20.63万
  • 财政年份:
    1987
  • 负责人:
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