BD Spokes: SPOKE: MIDWEST: Collaborative: Advanced Computational Neuroscience Network (ACNN)

新的神经科学工具和技术是必要的，以使深入了解神经回路的构建模块，这些回路之间的相互作用，支持人类大脑的功能，以及这些回路的调制，影响我们的行为。为了利用传感，成像和数据分析方面的快速技术发展，神经科学的新突破性进展对于使用数据科学方法促进知识发现是必要的。为了应对这一社会大挑战，该项目将促进跨计算，生物，数学和行为科学学科的新的跨学科合作，以及学术界，工业界和政府在多个层面的合作伙伴关系。名为中西部的大数据神经科学演讲：高级计算神经科学网络（ACNN）与神经科学的国家优先领域密切相关，并汇集了一系列致力于区域合作伙伴，使中西部地区能够实现大数据对神经科学的承诺。ACNN Spoke将就开发新一代可持续跨学科神经科学大数据研究所需的核心要求、基础设施和组件达成广泛共识。ACNN将利用中西部地区的优势和资源，通过在教育、工具和最佳实践方面的合作和服务，增加创新和合作，以了解人类大脑的结构、生理和功能。ACNN将设计、试验和支持强大的神经科学计算资源，用于高通量、协作和面向服务的数据聚合、处理和开放可再现科学。ACNN Spoke框架将解决与神经科学大数据相关的三个具体问题：（1）涉及多个中心和研究小组的数据捕获，组织和管理，（2）质量保证，包含上下文元数据的预处理和分析，以及（3）与软件和硬件计算资源的数据通信，可以随神经科学数据集的数量，速度和种类而扩展。ACNN将在学术界和工业界建立一个可持续的神经科学社区合作伙伴生态系统，利用现有技术进行协作和虚拟会议以及面对面的小组会议。ACNN Spoke的计划活动还将允许中西部大数据中心向神经科学界传播更多的大数据技术资源，包括访问超级计算设施，最佳实践和平台。该奖项获得了CISE高级网络基础设施（ACI）和信息与智能系统（IIS）部门的共同资助。

Novel neuroscience tools and techniques are necessary to enable insight into the building blocks of neural circuits, the interactions between these circuits that underpin the functions of the human brain, and modulation of these circuits that affect our behavior. To leverage rapid technological development in sensing, imaging, and data analysis new ground breaking advances in neuroscience are necessary to facilitate knowledge discovery using data science methods. To address this societal grand challenge, the project will foster new interdisciplinary collaborations across computing, biological, mathematical, and behavioral science disciplines together with partnerships in academia, industry, and government at multiple levels. The Big Data Neuroscience Spoke titled Midwest: Advanced Computational Neuroscience Network (ACNN) is strongly aligned with the national priority area of neuroscience and brings together a diverse set of committed regional partners to enable the Midwest region to realize the promise of Big Data for neuroscience. The ACNN Spoke will build broad consensus on the core requirements, infrastructure, and components needed to develop a new generation of sustainable interdisciplinary Neuroscience Big Data research. ACNN will leverage the strengths and resources in the Midwest region to increase innovation and collaboration for the understanding of the structure, physiology, and function of the human brain through partnerships and services in education, tools, and best practices. The ACNN will design, pilot and support powerful neuroscientific computational resources for high-throughput, collaborative, and service-oriented data aggregation, processing and open-reproducible science. The ACNN Spoke framework will address three specific problems related to neuroscience Big Data: (1) data capture, organization, and management involving multiple centers and research groups, (2) quality assurance, preprocessing and analysis that incorporates contextual metadata, and (3) data communication to software and hardware computational resources that can scale with the volume, velocity, and variety of neuroscience datasets. The ACNN will build a sustainable ecosystem of neuroscience community partners in both academia and industry using existing technologies for collaboration and virtual meeting together with face-to-face group meetings. The planned activities of the ACNN Spoke will also allow the Midwest Big Data Hub to disseminate additional Big Data technologies resources to the neuroscience community, including access to supercomputing facilities, best practices, and platforms.This award received co-funding from CISE Divisions of Advanced Cyberinfrastructure (ACI) and Information and Intelligent Systems (IIS).